C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: paired-like homeodomain transcription factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000174623 Pitx2-004 ENSMUSG00000028023 10090 + 3:129214275-129216624 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryENSMUST00000174623
Transcript ID Ovary
ENSMUST00000174623 0.137±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007P9 CIL_0007P9_0002 UCNEbase 3:127625906-129219414
CIL_0007RD CIL_0007RD_0002 VISTA 3:128625921-129227117
CIL_0007ZJ CIL_0007ZJ_0002 VISTA 3:128803805-129405710
CIL_000912 CIL_000912_0002 VISTA 3:128878432-129478935
CIL_000917 CIL_000917_0002 VISTA 3:128927194-129527766

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001569 IMP patterning of blood vessels
GO:0001570 IMP vasculogenesis
GO:0001701 IMP in utero embryonic development
GO:0001764 IMP neuron migration
GO:0002074 IMP extraocular skeletal muscle development
GO:0003171 IMP atrioventricular valve development
GO:0003350 IMP pulmonary myocardium development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007368 IMP determination of left/right symmetry
GO:0007507 IMP heart development
GO:0007519 IMP skeletal muscle tissue development
GO:0007520 IDA myoblast fusion
GO:0009653 IMP anatomical structure morphogenesis
GO:0009887 IMP organ morphogenesis
GO:0016055 IDA Wnt signaling pathway
GO:0021763 IMP subthalamic nucleus development
GO:0021855 IMP hypothalamus cell migration
GO:0021983 IMP pituitary gland development
GO:0030324 IMP lung development
GO:0030334 IMP regulation of cell migration
GO:0031076 IMP embryonic camera-type eye development
GO:0031490 IDA chromatin DNA binding
GO:0035116 IGI embryonic hindlimb morphogenesis
GO:0035886 IMP vascular smooth muscle cell differentiation
GO:0042127 IMP regulation of cell proliferation
GO:0042476 IMP odontogenesis
GO:0043388 IDA positive regulation of DNA binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048738 IMP cardiac muscle tissue development
GO:0055007 IMP cardiac muscle cell differentiation
GO:0055009 IMP atrial cardiac muscle tissue morphogenesis
GO:0055015 IMP ventricular cardiac muscle cell development
GO:0055123 IMP digestive system development
GO:0060412 IMP ventricular septum morphogenesis
GO:0060460 IMP left lung morphogenesis
GO:0060577 IMP pulmonary vein morphogenesis
GO:0060578 IMP superior vena cava morphogenesis
GO:0061031 IMP endodermal digestive tract morphogenesis
GO:0061325 IMP cell proliferation involved in outflow tract morphogenesis
GO:2000288 IDA positive regulation of myoblast proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000306732 PITX2-005 protein_coding Homo_sapiens 0 597
ENST00000354925 PITX2-003 protein_coding Homo_sapiens 0 287
ENST00000355080 PITX2-002 protein_coding Homo_sapiens 0 289
ENST00000394598 PITX2-001 protein_coding Homo_sapiens 0 287
ENST00000511837 PITX2-006 protein_coding Homo_sapiens 0 287
ENST00000511990 PITX2-007 protein_coding Homo_sapiens 0 289
ENST00000557119 PITX2-010 protein_coding Homo_sapiens 0 623
ENST00000613094 PITX2-201 protein_coding Homo_sapiens 0 287
ENST00000614423 PITX2-202 protein_coding Homo_sapiens 0 287
ENST00000616641 PITX2-203 protein_coding Homo_sapiens 0 289

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