C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000233202 SLC11A1-001 ENSG00000018280 9606 + 2:218382029-218396894 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLiverMuscleOvaryTestisENST00000233202
Transcript ID Adrenal Brain Breast Colon Heart Liver Muscle Ovary Testis
ENST00000233202 0.823±0.00 0.028±0.00 0.266±0.00 0.233±0.20 0.017±0.00 0.874±0.00 0.092±0.00 0.426±0.00 0.517±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00054V CIL_00054V_0001 CGP 2:218356856-218396894
CIL_0005VF CIL_0005VF_0001 CGP 2:218382029-218405941

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0001818 ISS negative regulation of cytokine production
GO:0001819 ISS positive regulation of cytokine production
GO:0002309 ISS T cell proliferation involved in immune response
GO:0002369 ISS T cell cytokine production
GO:0002606 ISS positive regulation of dendritic cell antigen processing and presentation
GO:0002827 ISS positive regulation of T-helper 1 type immune response
GO:0005215 IEA transporter activity
GO:0005384 ISS manganese ion transmembrane transporter activity
GO:0005764 ISS lysosome
GO:0005770 ISS late endosome
GO:0005886 IMP plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006810 IEA transport
GO:0006826 IMP iron ion transport
GO:0006828 ISS manganese ion transport
GO:0006876 IGI cellular cadmium ion homeostasis
GO:0006879 IMP cellular iron ion homeostasis
GO:0006909 ISS phagocytosis
GO:0006954 ISS inflammatory response
GO:0007035 ISS vacuolar acidification
GO:0009279 IEA cell outer membrane
GO:0009617 IDA response to bacterium
GO:0010008 IEA endosome membrane
GO:0010628 ISS positive regulation of gene expression
GO:0015707 ISS nitrite transport
GO:0016020 IEA membrane
GO:0030670 IDA phagocytic vesicle membrane
GO:0031902 TAS late endosome membrane
GO:0032147 ISS activation of protein kinase activity
GO:0032496 ISS response to lipopolysaccharide
GO:0032623 ISS interleukin-2 production
GO:0032632 ISS interleukin-3 production
GO:0032729 ISS positive regulation of interferon-gamma production
GO:0034341 ISS response to interferon-gamma
GO:0042060 ISS wound healing
GO:0042116 ISS macrophage activation
GO:0042742 ISS defense response to bacterium
GO:0042803 IDA protein homodimerization activity
GO:0042832 ISS defense response to protozoan
GO:0043091 ISS L-arginine import
GO:0045342 ISS MHC class II biosynthetic process
GO:0045730 ISS respiratory burst
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046915 IGI transition metal ion transmembrane transporter activity
GO:0048002 ISS antigen processing and presentation of peptide antigen
GO:0048255 ISS mRNA stabilization
GO:0050766 ISS positive regulation of phagocytosis
GO:0050829 ISS defense response to Gram-negative bacterium
GO:0051139 IGI metal ion:proton antiporter activity
GO:0051701 TAS interaction with host
GO:0055072 ISS iron ion homeostasis
GO:0055085 TAS transmembrane transport
GO:0060586 ISS multicellular organismal iron ion homeostasis
GO:0070574 IGI cadmium ion transmembrane transport
GO:0070821 IDA tertiary granule membrane
GO:0070839 ISS divalent metal ion export
GO:0071421 IEA manganese ion transmembrane transport
GO:0090382 TAS phagosome maturation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027368 Slc11a1-001 protein_coding Mus_musculus 0 1530
ENSMUST00000187516 Slc11a1-011 protein_coding Mus_musculus 0 1330
ENSMUST00000147233 Slc11a1-002 retained_intron Mus_musculus 0 1127
ENSMUST00000136786 Slc11a1-004 processed_transcript Mus_musculus 0 850
ENSMUST00000133896 Slc11a1-007 retained_intron Mus_musculus 0 525
ENSMUST00000131511 Slc11a1-003 retained_intron Mus_musculus 0 473
ENSMUST00000149166 Slc11a1-009 processed_transcript Mus_musculus 0 370
ENSMUST00000155865 Slc11a1-006 processed_transcript Mus_musculus 0 248
ENSMUST00000127487 Slc11a1-008 retained_intron Mus_musculus 0 217
ENSMUST00000135137 Slc11a1-005 processed_transcript Mus_musculus 7.00649e-45 187
ENSMUST00000186569 Ndufs1-004 retained_intron Mus_musculus 0.00007 55

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