C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tropomyosin 1 (alpha)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000267996 TPM1-005 ENSG00000140416 9606 + 15:63042758-63071915 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLiverLungOvaryTestisENST00000267996
Transcript ID Adipose Adrenal Brain Breast Colon Liver Lung Ovary Testis
ENST00000267996 42.146±0.00 168.608±0.00 7.965±0.00 97.883±0.00 187.550±2.70 420.956±0.00 20.527±8.49 54.006±27.32 54.828±42.88

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000502 CIL_000502_0002 CGP 15:62390526-63071915
CIL_00094O CIL_00094O_0001 VISTA 15:62748846-63351985
CIL_00098V CIL_00098V_0001 VISTA 15:62790346-63394142

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001725 IDA stress fiber
GO:0003065 ISS positive regulation of heart rate by epinephrine
GO:0003779 TAS actin binding
GO:0005200 TAS structural constituent of cytoskeleton
GO:0005829 TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0005862 TAS muscle thin filament tropomyosin
GO:0006928 TAS cellular component movement
GO:0006936 TAS muscle contraction
GO:0006937 TAS regulation of muscle contraction
GO:0007010 TAS cytoskeleton organization
GO:0008016 TAS regulation of heart contraction
GO:0008092 IPI cytoskeletal protein binding
GO:0008307 TAS structural constituent of muscle
GO:0030017 TAS sarcomere
GO:0030049 ISS muscle filament sliding
GO:0030336 ISS negative regulation of cell migration
GO:0031529 ISS ruffle organization
GO:0032059 IMP bleb
GO:0032587 IDA ruffle membrane
GO:0032781 ISS positive regulation of ATPase activity
GO:0034614 IEP cellular response to reactive oxygen species
GO:0042060 ISS wound healing
GO:0045214 IMP sarcomere organization
GO:0045785 ISS positive regulation of cell adhesion
GO:0051496 ISS positive regulation of stress fiber assembly
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113705 Tpm1-007 protein_coding Mus_musculus 0 1618
ENSMUST00000113701 Tpm1-010 protein_coding Mus_musculus 0 1441
ENSMUST00000113707 Tpm1-001 protein_coding Mus_musculus 0 1214
ENSMUST00000113695 Tpm1-016 protein_coding Mus_musculus 0 1210
ENSMUST00000034928 Tpm1-008 protein_coding Mus_musculus 0 1208
ENSMUST00000113696 Tpm1-015 protein_coding Mus_musculus 0 1053
ENSMUST00000113697 Tpm1-006 protein_coding Mus_musculus 0 1037
ENSMUST00000139046 Tpm1-017 nonsense_mediated_decay Mus_musculus 0 833
ENSMUST00000030185 Tpm1-002 protein_coding Mus_musculus 0 824
ENSMUST00000113687 Tpm1-012 protein_coding Mus_musculus 0 824
ENSMUST00000113686 Tpm1-014 protein_coding Mus_musculus 0 824
ENSMUST00000113685 Tpm1-003 protein_coding Mus_musculus 0 824
ENSMUST00000113693 Tpm1-011 protein_coding Mus_musculus 0 824
ENSMUST00000113690 Tpm1-013 protein_coding Mus_musculus 0 824
ENSMUST00000129733 Tpm1-009 nonsense_mediated_decay Mus_musculus 0 667
ENSMUST00000113684 Tpm1-020 protein_coding Mus_musculus 0 664
ENSMUST00000050905 Tpm1-004 protein_coding Mus_musculus 0 664
ENSMUST00000113689 Tpm1-021 protein_coding Mus_musculus 0 664
ENSDART00000039657 tpma-201 protein_coding Danio_rerio 0 579
ENSMUST00000129466 Tpm1-019 retained_intron Mus_musculus 0 503
ENSDART00000054763 tpma-202 protein_coding Danio_rerio 0 492
ENSMUST00000131279 Tpm1-018 processed_transcript Mus_musculus 0 381
ENSMUST00000107913 Tpm2-201 protein_coding Mus_musculus 0 374
ENSMUST00000107914 Tpm2-001 protein_coding Mus_musculus 0 320
ENSMUST00000030184 Tpm2-002 protein_coding Mus_musculus 0 307
ENSMUST00000150262 Tpm2-003 processed_transcript Mus_musculus 0 291
ENSMUST00000156899 Tpm1-005 processed_transcript Mus_musculus 1.4013e-45 189
ENSMUST00000150592 Tpm2-004 protein_coding Mus_musculus 2e-27 128

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