C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, ATPase, 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000310144 PSMC5-001 ENSG00000087191 9606 + 17:63827183-63832019 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartOvaryPlacentaENST00000310144
Transcript ID Heart Ovary Placenta
ENST00000310144 1.426±0.00 53.642±0.00 30.565±18.59

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0001 VISTA 17:63374232-63977730
CIL_0006Q4 CIL_0006Q4_0001 CGP 17:63773603-63830012
CIL_0006Q9 CIL_0006Q9_0001 CGP 17:63819433-63832026
CIL_0006QA CIL_0006QA_0001 CGP 17:63827152-63843065

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003712 TAS transcription cofactor activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005838 IEA proteasome regulatory particle
GO:0006200 IEA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008134 IPI transcription factor binding
GO:0009378 IEA four-way junction helicase activity
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016234 IEA inclusion body
GO:0016787 IEA hydrolase activity
GO:0016887 ISS:IEA ATPase activity
GO:0017025 IEA TBP-class protein binding
GO:0022624 ISS proteasome accessory complex
GO:0030163 IEA protein catabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031410 IDA cytoplasmic vesicle
GO:0031531 IPI thyrotropin-releasing hormone receptor binding
GO:0031595 IEA nuclear proteasome complex
GO:0031597 IEA cytosolic proteasome complex
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043069 NAS negative regulation of programmed cell death
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle
GO:0090261 IEA positive regulation of inclusion body assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021049 Psmc5-001 protein_coding Mus_musculus 0 1628
ENSMUST00000133131 Psmc5-002 nonsense_mediated_decay Mus_musculus 0 1282
ENSDART00000106191 psmc5-001 protein_coding Danio_rerio 0 1027

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