C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine hydroxymethyltransferase 1 (soluble)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018744 Shmt1-001 ENSMUSG00000020534 10090 - 11:60788104-60811265 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000018744
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000018744 3.531±0.57 13.576±5.35 4.516±0.26 4.018±1.28 4.156±0.22 8.832±0.56 1.507±0.22 28.666±8.07 43.736±18.03 2.840±0.46 6.599±0.88 10.973±5.19 4.751±1.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00002B CIL_00002B_0003 CGP 11:60740058-60788287
CIL_00058O CIL_00058O_0003 CGP 11:60777524-60811718

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004372 IEA glycine hydroxymethyltransferase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0006545 IEA glycine biosynthetic process
GO:0006565 IEA L-serine catabolic process
GO:0008732 IEA L-allo-threonine aldolase activity
GO:0009113 IEA purine nucleobase biosynthetic process
GO:0016597 IEA amino acid binding
GO:0019264 IEA glycine biosynthetic process from serine
GO:0030170 IEA pyridoxal phosphate binding
GO:0035999 IEA tetrahydrofolate interconversion
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0046655 IEA folic acid metabolic process
GO:0051262 IEA protein tetramerization
GO:0051289 IEA protein homotetramerization
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000316694 SHMT1-001 protein_coding Homo_sapiens 0 1483
ENST00000352886 SHMT1-201 protein_coding Homo_sapiens 0 1155
ENST00000354098 SHMT1-003 protein_coding Homo_sapiens 0 905
ENST00000395682 SHMT1-005 retained_intron Homo_sapiens 0 248
ENST00000395684 SHMT1-004 retained_intron Homo_sapiens 0 952
ENST00000419974 SHMT1P1-001 processed_pseudogene Homo_sapiens 0 1140
ENST00000579558 SHMT1-008 retained_intron Homo_sapiens 0 656
ENST00000580002 SHMT1-006 nonsense_mediated_decay Homo_sapiens 0 1155
ENST00000582653 SHMT1-009 protein_coding Homo_sapiens 0 520

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