C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DNA (cytosine-5-)-methyltransferase 3 beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000328111 DNMT3B-001 ENSG00000088305 9606 + 20:32762385-32809356 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartOvaryPlacentaENST00000328111
Transcript ID Heart Ovary Placenta
ENST00000328111 0.047±0.00 1.457±0.00 0.608±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A4 CIL_0008A4_0001 VISTA 20:32224531-32829311
CIL_0008NQ CIL_0008NQ_0001 VISTA 20:32326689-32928341
CIL_0008QN CIL_0008QN_0001 VISTA 20:32676112-33281064
CIL_00036W CIL_00036W_0001 CGP 20:32702691-32809356
CIL_0001KC CIL_0001KC_0001 CGP 20:32762385-32850405

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000792 IEA heterochromatin
GO:0003677 IEA DNA binding
GO:0003714 IDA transcription corepressor activity
GO:0003886 TAS DNA (cytosine-5-)-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005720 IEA nuclear heterochromatin
GO:0005737 IEA cytoplasm
GO:0006306 TAS DNA methylation
GO:0006346 IEA methylation-dependent chromatin silencing
GO:0006349 IEA regulation of gene expression by genetic imprinting
GO:0008168 IEA methyltransferase activity
GO:0009008 NAS DNA-methyltransferase activity
GO:0010212 IEA response to ionizing radiation
GO:0010424 IEA DNA methylation on cytosine within a CG sequence
GO:0010628 IMP positive regulation of gene expression
GO:0031503 IEA protein complex localization
GO:0042493 IEA response to drug
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045322 IEA unmethylated CpG binding
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046499 IEA S-adenosylmethioninamine metabolic process
GO:0046872 IEA metal ion binding
GO:0051571 IMP positive regulation of histone H3-K4 methylation
GO:0051573 IMP negative regulation of histone H3-K9 methylation
GO:0051718 IEA DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
GO:0071230 IEA cellular response to amino acid stimulus
GO:0090116 IEA C-5 methylation of cytosine

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109774 Dnmt3b-001 protein_coding Mus_musculus 0 2170
ENSMUST00000072997 Dnmt3b-002 protein_coding Mus_musculus 0 2170
ENSMUST00000056495 Dnmt3b-201 protein_coding Mus_musculus 0 2163
ENSMUST00000109771 Dnmt3b-009 protein_coding Mus_musculus 0 2163
ENSMUST00000109772 Dnmt3b-007 protein_coding Mus_musculus 0 1631
ENSMUST00000088976 Dnmt3b-005 protein_coding Mus_musculus 0 1631
ENSMUST00000081628 Dnmt3b-004 protein_coding Mus_musculus 0 1511
ENSMUST00000109773 Dnmt3b-003 protein_coding Mus_musculus 0 1511
ENSMUST00000119996 Gm14490-001 unprocessed_pseudogene Mus_musculus 0 1395
ENSMUST00000103150 Dnmt3b-008 protein_coding Mus_musculus 0 597
ENSMUST00000103151 Dnmt3b-006 protein_coding Mus_musculus 0 597
ENSMUST00000132132 Dnmt3b-010 retained_intron Mus_musculus 0 265

Loading