C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000337665 ARHGEF1-006 ENSG00000076928 9606 + 19:41884448-41907454 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverOvaryPlacentaTestisENST00000337665
Transcript ID Kidney Liver Ovary Placenta Testis
ENST00000337665 0.818±0.00 1.837±0.00 8.133±6.22 15.351±5.41 3.860±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003UK CIL_0003UK_0002 CGP 19:41877120-41930150
CIL_0003VE CIL_0003VE_0001 CGP 19:41883161-41959390

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007266 TAS Rho protein signal transduction
GO:0008283 TAS cell proliferation
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0044822 IDA poly(A) RNA binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050770 TAS regulation of axonogenesis
GO:0050771 TAS negative regulation of axonogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000117419 Arhgef1-006 protein_coding Mus_musculus 0 3177
ENSMUST00000047873 Arhgef1-003 protein_coding Mus_musculus 0 3168
ENSMUST00000145783 Arhgef1-005 processed_transcript Mus_musculus 0 2080
ENSMUST00000098683 Arhgef1-001 protein_coding Mus_musculus 0 2080
ENSMUST00000117796 Arhgef1-002 protein_coding Mus_musculus 0 2080
ENSMUST00000132751 Arhgef1-008 protein_coding Mus_musculus 0 1700
ENSMUST00000132786 Arhgef1-015 processed_transcript Mus_musculus 0 789
ENSMUST00000144714 Arhgef1-011 retained_intron Mus_musculus 0 599
ENSMUST00000151121 Arhgef1-010 protein_coding Mus_musculus 0 368
ENSMUST00000126918 Arhgef1-014 retained_intron Mus_musculus 0 348
ENSMUST00000126484 Arhgef1-013 retained_intron Mus_musculus 0 315
ENSMUST00000127761 Arhgef1-004 retained_intron Mus_musculus 0 267

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