C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368884 PSMD4-001 ENSG00000159352 9606 + 1:151254703-151267479 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368884
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368884 25.269±0.00 29.201±0.00 7.689±0.00 40.306±6.42 23.104±3.12 27.519±13.76 16.667±4.48 21.339±2.72 26.786±2.01 16.049±2.50 83.267±43.05 51.065±23.39 84.209±12.08 73.652±16.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LW CIL_0000LW_0003 CGP 1:151197949-151267479

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008540 IEA proteasome regulatory particle, base subcomplex
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0022624 ISS proteasome accessory complex
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042802 IPI identical protein binding
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107237 Psmd4-002 protein_coding Mus_musculus 0 1561
ENSMUST00000071664 Psmd4-001 protein_coding Mus_musculus 0 1487
ENSMUST00000117355 Psmd4-004 protein_coding Mus_musculus 0 1229
ENSMUST00000136868 Psmd4-005 retained_intron Mus_musculus 0 1170
ENSMUST00000140348 Psmd4-008 protein_coding Mus_musculus 0 579
ENSMUST00000140280 Psmd4-003 retained_intron Mus_musculus 0 518

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