C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activating transcription factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000426833 ATF2-201 ENSG00000115966 9606 - 2:175072254-175168206 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastHeartLiverLungMuscleENST00000426833
Transcript ID Adrenal Brain Breast Heart Liver Lung Muscle
ENST00000426833 0.782±0.00 3.611±0.00 2.727±0.00 2.362±0.00 1.619±0.00 4.065±0.00 0.268±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001HB CIL_0001HB_0001 CGP 2:174799363-175168382
CIL_0001H6 CIL_0001H6_0001 CGP 2:175072250-175184607

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000977 IMP RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001076 IC RNA polymerase II transcription factor binding transcription factor activity
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001228 IC RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IC RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 TAS transcription coactivator activity
GO:0004402 IDA histone acetyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005741 IDA mitochondrial outer membrane
GO:0006325 TAS chromatin organization
GO:0006355 IMP:IEA regulation of transcription, DNA-templated
GO:0006357 IC regulation of transcription from RNA polymerase II promoter
GO:0006366 IC transcription from RNA polymerase II promoter
GO:0006970 IDA response to osmotic stress
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0008140 IDA cAMP response element binding protein binding
GO:0016573 IEA histone acetylation
GO:0019901 IPI protein kinase binding
GO:0031573 IMP intra-S DNA damage checkpoint
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035497 IDA cAMP response element binding
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0035861 IDA site of double-strand break
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade
GO:1902110 IMP positive regulation of mitochondrial membrane permeability involved in apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000100009 Atf2-201 protein_coding Mus_musculus 0 3325
ENSMUST00000055833 Atf2-005 protein_coding Mus_musculus 0 3325
ENSMUST00000112007 Atf2-002 protein_coding Mus_musculus 0 3053
ENSMUST00000090802 Atf2-006 protein_coding Mus_musculus 0 3053
ENSMUST00000112010 Atf2-008 protein_coding Mus_musculus 0 3053
ENSMUST00000112017 Atf2-202 protein_coding Mus_musculus 0 2926
ENSMUST00000156455 Atf2-007 processed_transcript Mus_musculus 0 2174
ENSMUST00000112016 Atf2-001 protein_coding Mus_musculus 0 2174
ENSMUST00000143714 Atf2-004 processed_transcript Mus_musculus 0 1794
ENSMUST00000173010 Atf2-017 nonsense_mediated_decay Mus_musculus 0 1794
ENSMUST00000124737 Atf2-015 protein_coding Mus_musculus 0 1358
ENSMUST00000141050 Atf2-003 processed_transcript Mus_musculus 0 1151
ENSMUST00000128531 Atf2-011 protein_coding Mus_musculus 0 1149
ENSMUST00000136958 Atf2-013 protein_coding Mus_musculus 0 647
ENSMUST00000154456 Atf2-016 protein_coding Mus_musculus 0 505
ENSMUST00000129555 Atf2-014 processed_transcript Mus_musculus 0 333
ENSMUST00000125159 Atf2-009 processed_transcript Mus_musculus 0 211
ENSMUST00000138098 Atf2-010 processed_transcript Mus_musculus 3e-18 99

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