C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: high mobility group box 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000029993 HMGB3 9606 + X:150980509-150990775 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000325307 HMGB3-001 150983286-150990775 protein_coding
  ENST00000419110 HMGB3-002 150980509-150987877 protein_coding
  ENST00000430118 HMGB3-004 150985531-150987297 protein_coding
  ENST00000448905 HMGB3-201 150983406-150987932 protein_coding
  ENST00000455596 HMGB3-003 150983385-150987892 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000325307ENST00000419110ENST00000430118ENST00000448905ENST00000455596
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000325307 1.815±0.00 1.773±0.00 3.373±1.82 1.079±0.73 1.317±0.22 0.577±0.00 1.841±0.60 3.411±2.94 0.922±0.56 2.158±2.06 1.903±1.06 30.917±11.80 4.492±1.12
ENST00000419110 N/A N/A 3.283±0.00 0.893±0.00 3.452±0.00 N/A 3.299±0.00 0.761±0.00 1.043±0.00 N/A N/A N/A 6.916±0.00
ENST00000430118 N/A N/A N/A 4.327±0.00 N/A N/A N/A N/A N/A N/A 6.052±4.17 52.974±0.00 18.497±0.00
ENST00000448905 3.597±0.00 3.026±0.00 5.754±0.00 N/A N/A 1.153±0.00 N/A 10.267±0.00 2.096±0.00 N/A N/A N/A 8.005±0.00
ENST00000455596 N/A N/A N/A N/A N/A N/A N/A N/A 2.245±0.00 3.805±0.00 5.237±0.88 97.916±34.82 14.348±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000UN CIL_0000UN_0002 CGP X:150766337-150990775
CIL_0009DG CIL_0009DG_0001 VISTA X:150939220-151540580
CIL_0001AV CIL_0001AV_0001 CGP X:150980509-151181465

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003690 ISS double-stranded DNA binding
GO:0005634 IEA nucleus
GO:0005694 IEA chromosome
GO:0006310 ISS DNA recombination
GO:0007275 TAS multicellular organismal development
GO:0008301 ISS DNA binding, bending
GO:0044822 IDA poly(A) RNA binding
GO:0045578 IEA negative regulation of B cell differentiation
GO:0045638 IEA negative regulation of myeloid cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006408 hmgb3b high-mobility group box 3b protein_coding Danio_rerio
ENSDARG00000056725 hmgb3a high-mobility group box 3a protein_coding Danio_rerio
ENSMUSG00000015217 Hmgb3 high mobility group box 3 protein_coding Mus_musculus

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