C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actin, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000075624 ACTB 9606 - 7:5527151-5563784 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331789 ACTB-001 5527151-5530709 protein_coding
  ENST00000414620 ACTB-010 5529282-5562790 protein_coding
  ENST00000417101 ACTB-012 5529235-5529982 protein_coding
  ENST00000425660 ACTB-002 5527156-5530601 nonsense_mediated_decay
  ENST00000432588 ACTB-008 5528592-5563784 protein_coding
  ENST00000443528 ACTB-009 5529216-5562828 protein_coding
  ENST00000462494 ACTB-003 5527156-5530601 retained_intron
  ENST00000464611 ACTB-013 5527151-5528098 processed_transcript
  ENST00000473257 ACTB-011 5528150-5530604 processed_transcript
  ENST00000477812 ACTB-007 5528470-5530590 retained_intron
  ENST00000480301 ACTB-006 5529067-5530583 retained_intron
  ENST00000484841 ACTB-005 5528111-5530602 retained_intron
  ENST00000493945 ACTB-004 5527741-5529663 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331789ENST00000425660ENST00000462494ENST00000464611ENST00000484841
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331789 1636.060±0.00 1512.510±0.00 13.539±0.00 376.087±112.04 599.363±330.71 1059.447±713.45 152.877±123.45 284.813±196.38 464.973±67.08 1222.303±1089.61 265.266±0.00 1345.335±833.45 2236.070±366.46 445.220±116.42
ENST00000425660 N/A N/A 46.065±0.00 N/A 62.947±0.00 84.810±0.00 10.236±0.00 N/A N/A 70.874±0.00 39.685±0.00 103.893±0.00 N/A N/A
ENST00000462494 N/A N/A 12.127±0.00 N/A N/A N/A 6.613±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000464611 3204.210±0.00 3235.960±0.00 N/A 1686.100±0.00 2361.360±0.00 4399.980±0.00 223.468±0.00 1168.960±0.00 747.063±0.00 2389.490±0.00 251.487±0.00 2956.070±0.00 N/A 2154.970±0.00
ENST00000484841 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 213.901±0.00 625.078±0.00 1302.230±0.00 148.239±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000854 CIL_000854_0001 VISTA 7:5332287-5936913
CIL_0002V9 CIL_0002V9_0001 CGP 7:5431335-5563784
CIL_0002V8 CIL_0002V8_0001 CGP 7:5527151-5606655

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001895 IEP retina homeostasis
GO:0005200 TAS structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0005925 IDA focal adhesion
GO:0006325 TAS chromatin organization
GO:0006457 TAS protein folding
GO:0006928 TAS cellular component movement
GO:0007409 IEA axonogenesis
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0014069 IEA postsynaptic density
GO:0016020 IDA membrane
GO:0019894 IPI kinesin binding
GO:0019901 IEA protein kinase binding
GO:0021762 IEP substantia nigra development
GO:0030424 IEA axon
GO:0030529 IDA ribonucleoprotein complex
GO:0030863 IEA cortical cytoskeleton
GO:0030957 IPI Tat protein binding
GO:0031492 IDA nucleosomal DNA binding
GO:0034329 TAS cell junction assembly
GO:0034332 TAS adherens junction organization
GO:0035267 IDA NuA4 histone acetyltransferase complex
GO:0036464 IDA cytoplasmic ribonucleoprotein granule
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043044 IDA ATP-dependent chromatin remodeling
GO:0043234 IDA protein complex
GO:0044267 TAS cellular protein metabolic process
GO:0045087 TAS innate immune response
GO:0045216 TAS cell-cell junction organization
GO:0050998 IPI nitric-oxide synthase binding
GO:0051084 TAS 'de novo' posttranslational protein folding
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IMP platelet aggregation
GO:0070688 IDA MLL5-L complex
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029580 Actb actin, beta protein_coding Mus_musculus

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