C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: poly(A) polymerase alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000090060 PAPOLA 9606 + 14:96501433-96567111 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216277 PAPOLA-001 96502373-96567111 protein_coding
  ENST00000392990 PAPOLA-005 96502558-96565428 protein_coding
  ENST00000553357 PAPOLA-011 96502382-96532338 nonsense_mediated_decay
  ENST00000553461 PAPOLA-025 96527442-96534889 protein_coding
  ENST00000553689 PAPOLA-003 96502398-96565048 nonsense_mediated_decay
  ENST00000553940 PAPOLA-021 96560438-96565059 retained_intron
  ENST00000554130 PAPOLA-012 96502412-96531728 processed_transcript
  ENST00000554135 PAPOLA-019 96547688-96552983 retained_intron
  ENST00000554666 PAPOLA-026 96536895-96547904 retained_intron
  ENST00000554887 PAPOLA-010 96501433-96527496 processed_transcript
  ENST00000555021 PAPOLA-016 96535525-96537047 retained_intron
  ENST00000555131 PAPOLA-015 96534223-96537059 retained_intron
  ENST00000555224 PAPOLA-024 96521063-96532696 retained_intron
  ENST00000555508 PAPOLA-022 96562458-96565106 retained_intron
  ENST00000555626 PAPOLA-006 96502851-96564988 protein_coding
  ENST00000555701 PAPOLA-009 96542182-96553532 retained_intron
  ENST00000555912 PAPOLA-007 96525981-96531725 retained_intron
  ENST00000556248 PAPOLA-014 96504289-96521072 processed_transcript
  ENST00000556283 PAPOLA-018 96542729-96555950 retained_intron
  ENST00000556459 PAPOLA-020 96547896-96565407 protein_coding
  ENST00000556619 PAPOLA-013 96502542-96528002 protein_coding
  ENST00000556787 PAPOLA-017 96541907-96552543 retained_intron
  ENST00000557320 PAPOLA-002 96502401-96534885 protein_coding
  ENST00000557406 PAPOLA-023 96521016-96531731 retained_intron
  ENST00000557471 PAPOLA-004 96502441-96532248 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216277ENST00000554130ENST00000554887ENST00000557320
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216277 20.531±0.00 18.137±0.00 3.182±0.00 5.956±0.00 13.355±2.89 18.145±12.79 11.530±7.85 11.066±3.94 11.549±0.66 9.829±5.43 11.517±0.00 19.003±8.73 15.807±1.15 27.001±10.64
ENST00000554130 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 33.644±0.00 49.591±0.00 92.679±0.00
ENST00000554887 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 31.502±0.00 45.019±0.00 86.347±0.00
ENST00000557320 N/A N/A 3.073±0.00 7.358±0.85 7.814±0.00 6.279±0.00 3.186±0.00 N/A N/A 7.994±2.02 2.216±0.00 6.017±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HI CIL_0003HI_0001 CGP 14:96392111-96567111
CIL_0003HJ CIL_0003HJ_0001 CGP 14:96501433-96931722

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003723 IEA RNA binding
GO:0004652 ISS:IEA polynucleotide adenylyltransferase activity
GO:0005524 ISS ATP binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016779 IEA nucleotidyltransferase activity
GO:0030145 ISS manganese ion binding
GO:0031123 IEA RNA 3'-end processing
GO:0031124 TAS mRNA 3'-end processing
GO:0043631 ISS:IEA RNA polyadenylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009585 papola poly(A) polymerase alpha protein_coding Danio_rerio
ENSMUSG00000021111 Papola poly (A) polymerase alpha protein_coding Mus_musculus

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