C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: poly (A) polymerase alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021111 Papola 10090 + 12:105784694-105838944 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021535 Papola-003 105784704-105838939 nonsense_mediated_decay
  ENSMUST00000109901 Papola-001 105784694-105838807 protein_coding
  ENSMUST00000163473 Papola-009 105784716-105837131 protein_coding
  ENSMUST00000163805 Papola-006 105799685-105811412 retained_intron
  ENSMUST00000164326 Papola-014 105784745-105806589 nonsense_mediated_decay
  ENSMUST00000164798 Papola-019 105812351-105829246 protein_coding
  ENSMUST00000165584 Papola-013 105784740-105809709 processed_transcript
  ENSMUST00000166329 Papola-008 105784738-105836858 nonsense_mediated_decay
  ENSMUST00000166471 Papola-011 105812300-105837110 protein_coding
  ENSMUST00000166498 Papola-005 105784733-105814069 retained_intron
  ENSMUST00000166735 Papola-007 105784757-105809709 protein_coding
  ENSMUST00000168186 Papola-002 105784704-105834893 protein_coding
  ENSMUST00000169524 Papola-017 105808614-105820379 nonsense_mediated_decay
  ENSMUST00000169938 Papola-004 105784743-105838944 nonsense_mediated_decay
  ENSMUST00000170002 Papola-010 105784872-105837273 protein_coding
  ENSMUST00000170189 Papola-018 105817880-105818830 retained_intron
  ENSMUST00000170540 Papola-015 105784746-105809647 protein_coding
  ENSMUST00000170831 Papola-016 105809324-105809709 retained_intron
  ENSMUST00000172040 Papola-012 105784711-105809547 processed_transcript
  ENSMUST00000172089 Papola-020 105829067-105835499 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000109901ENSMUST00000164326ENSMUST00000166471ENSMUST00000166735ENSMUST00000168186ENSMUST00000169938ENSMUST00000170540ENSMUST00000172040
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000109901 15.366±4.60 14.473±2.66 18.514±0.00 13.327±10.56 15.782±6.14 20.729±4.77 10.151±1.74 20.253±1.41 16.450±8.18 17.963±4.08 4.215±0.61 25.387±6.13 22.099±8.83 19.914±8.76
ENSMUST00000164326 N/A 38.153±12.87 N/A N/A 25.714±4.82 36.781±12.40 N/A N/A 20.412±1.82 37.525±0.00 N/A 49.813±13.74 N/A 46.551±0.00
ENSMUST00000166471 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.903±0.00
ENSMUST00000166735 N/A 26.112±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 44.101±0.00 N/A
ENSMUST00000168186 N/A 8.313±2.29 N/A N/A N/A 9.890±1.72 N/A N/A N/A N/A N/A 13.050±3.54 N/A 15.192±2.46
ENSMUST00000169938 4.633±0.05 N/A 11.622±3.64 24.696±5.51 6.537±0.00 N/A 6.426±1.61 7.002±1.67 11.959±6.79 6.001±1.19 3.341±0.30 7.361±1.16 13.006±5.10 6.936±0.00
ENSMUST00000170540 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 72.757±0.00 N/A
ENSMUST00000172040 N/A N/A N/A 24.033±0.00 N/A N/A N/A N/A N/A N/A N/A 96.870±0.00 127.003±1.41 53.412±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HI CIL_0003HI_0002 CGP 12:105705982-105838944
CIL_0003HJ CIL_0003HJ_0002 CGP 12:105784694-106077410

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0000398 IBA mRNA splicing, via spliceosome
GO:0003723 IEA RNA binding
GO:0004652 IDA:ISS polynucleotide adenylyltransferase activity
GO:0005524 ISS ATP binding
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0006369 IBA termination of RNA polymerase II transcription
GO:0006378 IBA mRNA polyadenylation
GO:0030145 ISS manganese ion binding
GO:0043631 IDA:ISS RNA polyadenylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009585 papola poly(A) polymerase alpha protein_coding Danio_rerio
ENSG00000090060 PAPOLA poly(A) polymerase alpha protein_coding Homo_sapiens

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