C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein L, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100342 APOL1 9606 + 22:36253010-36267530 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000319136 APOL1-003 36253078-36267521 protein_coding
  ENST00000397278 APOL1-001 36253010-36267525 protein_coding
  ENST00000397279 APOL1-201 36253141-36267083 protein_coding
  ENST00000422471 APOL1-008 36253131-36261673 nonsense_mediated_decay
  ENST00000422706 APOL1-202 36253071-36267530 protein_coding
  ENST00000426053 APOL1-203 36253071-36267530 protein_coding
  ENST00000427990 APOL1-011 36253133-36265315 protein_coding
  ENST00000431184 APOL1-014 36253164-36261633 nonsense_mediated_decay
  ENST00000433768 APOL1-013 36253161-36261644 protein_coding
  ENST00000438034 APOL1-009 36253133-36261675 protein_coding
  ENST00000439680 APOL1-012 36253133-36261699 nonsense_mediated_decay
  ENST00000475519 APOL1-010 36253133-36257560 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000319136ENST00000397278ENST00000397279ENST00000422706ENST00000426053ENST00000427990
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000319136 N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.926±0.00 N/A N/A N/A N/A
ENST00000397278 N/A N/A 0.799±0.00 N/A 1.991±0.00 0.781±0.00 0.243±0.00 6.045±2.84 7.735±5.85 10.834±9.01 N/A 8.908±5.45 28.542±2.94 N/A
ENST00000397279 7.976±0.00 N/A 2.742±0.00 1.616±1.37 5.130±0.49 5.237±3.83 2.608±1.92 9.392±1.27 4.312±0.00 3.264±0.00 2.686±0.00 6.709±3.59 15.762±0.00 8.742±0.00
ENST00000422706 3.111±0.00 10.224±0.00 N/A 0.259±0.00 8.278±0.00 12.313±0.00 4.511±0.00 6.720±0.00 N/A 16.633±0.00 N/A 4.950±0.00 6.940±0.00 4.365±3.33
ENST00000426053 13.351±0.00 12.778±0.00 N/A 2.469±0.00 6.794±0.00 9.780±0.00 1.806±1.62 14.949±0.00 N/A N/A 1.488±0.92 12.801±4.46 17.948±9.31 7.064±5.16
ENST00000427990 N/A N/A N/A N/A N/A 2.538±0.00 0.910±0.00 22.247±0.00 N/A N/A 1.055±0.00 2.441±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003GS CIL_0003GS_0003 CGP 22:36226203-36267530
CIL_0003GV CIL_0003GV_0001 CGP 22:36253010-36388018

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005254 IDA chloride channel activity
GO:0005515 IPI protein binding
GO:0005576 IEA:TAS extracellular region
GO:0005615 IDA extracellular space
GO:0006821 IDA chloride transport
GO:0006869 IEA lipid transport
GO:0008203 IEA cholesterol metabolic process
GO:0008289 IEA:IDA lipid binding
GO:0019835 IDA cytolysis
GO:0031224 IC intrinsic component of membrane
GO:0031640 IDA killing of cells of other organism
GO:0034361 IDA very-low-density lipoprotein particle
GO:0034364 IDA high-density lipoprotein particle
GO:0042157 IEA lipoprotein metabolic process
GO:0045087 IDA innate immune response
GO:0072562 IDA blood microparticle
GO:1902476 IDA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073718 APOL4 apolipoprotein L, 4 protein_coding Danio_rerio
ENSMUSG00000010601 Apol7a apolipoprotein L 7a protein_coding Mus_musculus
ENSMUSG00000044309 Apol7c apolipoprotein L 7c protein_coding Mus_musculus
ENSMUSG00000050014 Apol10b apolipoprotein L 10B protein_coding Mus_musculus
ENSMUSG00000050982 Apol10a apolipoprotein L 10A protein_coding Mus_musculus
ENSMUSG00000056656 Apol8 apolipoprotein L 8 protein_coding Mus_musculus
ENSMUSG00000057346 Apol9a apolipoprotein L 9a protein_coding Mus_musculus
ENSMUSG00000068246 Apol9b apolipoprotein L 9b protein_coding Mus_musculus
ENSMUSG00000068252 Apol7b apolipoprotein L 7b protein_coding Mus_musculus
ENSMUSG00000071716 Apol7e apolipoprotein L 7e protein_coding Mus_musculus
ENSMUSG00000091650 Apol11a apolipoprotein L 11a protein_coding Mus_musculus
ENSMUSG00000091694 Apol11b apolipoprotein L 11b protein_coding Mus_musculus

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