C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/arginine-rich splicing factor 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100650 SRSF5 9606 + 14:69726900-69772005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000394366 SRSF5-005 69767093-69771973 protein_coding
  ENST00000553369 SRSF5-018 69767112-69769594 protein_coding
  ENST00000553521 SRSF5-003 69726900-69772004 protein_coding
  ENST00000553548 SRSF5-016 69767112-69769189 protein_coding
  ENST00000553635 SRSF5-004 69767157-69771949 protein_coding
  ENST00000554021 SRSF5-010 69767940-69769644 protein_coding
  ENST00000554465 SRSF5-001 69767093-69772004 retained_intron
  ENST00000554929 SRSF5-008 69770881-69771915 retained_intron
  ENST00000555349 SRSF5-011 69767940-69769383 protein_coding
  ENST00000555412 SRSF5-009 69767783-69768675 retained_intron
  ENST00000555547 SRSF5-007 69767186-69771654 nonsense_mediated_decay
  ENST00000556184 SRSF5-006 69767172-69771642 retained_intron
  ENST00000556330 SRSF5-014 69769746-69771257 retained_intron
  ENST00000556436 SRSF5-017 69767240-69768928 retained_intron
  ENST00000556587 SRSF5-019 69767182-69772005 processed_transcript
  ENST00000556647 SRSF5-013 69770448-69772005 processed_transcript
  ENST00000557154 SRSF5-002 69767124-69771991 protein_coding
  ENST00000557435 SRSF5-012 69767116-69768619 retained_intron
  ENST00000557460 SRSF5-015 69767175-69771108 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394366ENST00000553369ENST00000553548ENST00000553635ENST00000554465ENST00000555547ENST00000556184ENST00000556330ENST00000556587ENST00000556647ENST00000557154
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394366 N/A N/A N/A 45.639±0.00 N/A N/A N/A N/A N/A 16.103±0.00 3.322±0.00 32.970±0.00 N/A N/A
ENST00000553369 53.480±0.00 130.681±0.00 N/A 162.545±0.00 N/A 11.757±0.00 27.806±0.00 N/A N/A N/A N/A 32.776±0.00 49.647±0.00 32.042±0.00
ENST00000553548 N/A N/A 33.574±0.00 24.285±0.00 N/A N/A 10.897±0.00 N/A 44.350±0.00 N/A N/A 46.304±19.72 92.236±0.00 174.729±0.00
ENST00000553635 N/A N/A N/A N/A N/A N/A 13.742±0.00 N/A 11.668±0.00 N/A N/A 29.772±0.00 10.278±2.98 N/A
ENST00000554465 N/A N/A N/A N/A N/A 6.373±0.00 N/A N/A N/A 10.217±0.00 N/A N/A N/A N/A
ENST00000555547 N/A N/A N/A N/A N/A 2.034±0.00 8.563±0.00 N/A 6.583±0.00 15.473±0.00 2.999±0.27 32.298±8.02 6.903±0.33 61.825±0.00
ENST00000556184 7.198±0.00 N/A 19.945±0.00 14.185±0.00 17.920±5.59 14.406±11.68 5.846±1.18 18.252±1.37 20.770±0.00 21.585±11.77 N/A 15.932±2.72 4.157±0.00 17.747±11.81
ENST00000556330 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.349±1.03 N/A N/A N/A
ENST00000556587 N/A N/A N/A N/A N/A 2.621±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000556647 35.292±0.00 118.958±0.00 N/A 64.606±41.03 67.017±0.00 9.043±0.00 22.687±0.00 44.403±13.58 36.509±0.00 47.131±0.00 9.426±2.85 104.816±0.00 26.613±2.06 30.067±0.00
ENST00000557154 25.645±0.00 63.846±0.00 N/A 7.888±0.00 27.781±12.71 2.727±0.00 3.516±0.00 20.545±0.00 7.913±0.00 N/A 2.266±0.00 40.936±28.85 14.010±1.41 15.435±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002M1 CIL_0002M1_0001 CGP 14:69611596-69772005
CIL_0000U3 CIL_0000U3_0001 CGP 14:69726900-69797289

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006376 TAS mRNA splice site selection
GO:0006397 TAS mRNA processing
GO:0006406 TAS mRNA export from nucleus
GO:0008380 TAS RNA splicing
GO:0009611 IEA response to wounding
GO:0010467 TAS gene expression
GO:0016607 ISS nuclear speck
GO:0031124 TAS mRNA 3'-end processing
GO:0044822 IDA poly(A) RNA binding
GO:0050733 IEA RS domain binding
GO:0051726 IEA regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027734 srsf5b serine/arginine-rich splicing factor 5b protein_coding Danio_rerio
ENSMUSG00000021134 Srsf5 serine/arginine-rich splicing factor 5 protein_coding Mus_musculus

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