C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, AMPA 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120251 GRIA2 9606 + 4:157204182-157366075 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264426 GRIA2-002 157220764-157363945 protein_coding
  ENST00000296526 GRIA2-001 157220718-157366075 protein_coding
  ENST00000323661 GRIA2-006 157221242-157362821 nonsense_mediated_decay
  ENST00000393815 GRIA2-004 157220668-157366069 protein_coding
  ENST00000471736 GRIA2-003 157220724-157364287 retained_intron
  ENST00000503437 GRIA2-014 157249464-157317686 protein_coding
  ENST00000503980 GRIA2-013 157360700-157362934 retained_intron
  ENST00000504801 GRIA2-007 157204182-157303705 processed_transcript
  ENST00000505888 GRIA2-011 157221598-157312786 protein_coding
  ENST00000506284 GRIA2-010 157220807-157303634 protein_coding
  ENST00000507898 GRIA2-005 157220143-157363684 protein_coding
  ENST00000509417 GRIA2-009 157220691-157303696 protein_coding
  ENST00000510854 GRIA2-012 157341429-157363164 protein_coding
  ENST00000512774 GRIA2-008 157219903-157221723 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264426ENST00000296526ENST00000323661ENST00000393815ENST00000471736ENST00000503437ENST00000504801ENST00000505888ENST00000506284ENST00000507898ENST00000509417ENST00000510854
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264426 0.018±0.00 N/A N/A 15.251±1.20 N/A N/A 0.046±0.00 N/A N/A N/A 0.233±0.18 N/A 0.212±0.00
ENST00000296526 N/A N/A N/A 10.539±4.43 N/A N/A N/A N/A N/A 0.089±0.00 0.091±0.00 N/A 0.079±0.00
ENST00000323661 N/A N/A N/A N/A 0.051±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000393815 N/A 0.012±0.00 0.136±0.00 9.872±0.00 0.007±0.00 N/A 0.044±0.00 N/A 0.076±0.00 N/A 0.088±0.00 0.048±0.00 0.099±0.00
ENST00000471736 N/A N/A N/A 12.508±0.00 0.038±0.00 0.014±0.00 N/A 0.307±0.00 N/A N/A 0.029±0.00 N/A 0.076±0.00
ENST00000503437 N/A N/A N/A N/A N/A 0.030±0.00 N/A N/A N/A 1.971±0.00 N/A 0.101±0.00 1.028±0.00
ENST00000504801 N/A N/A N/A N/A N/A N/A N/A N/A 0.788±0.00 N/A N/A N/A N/A
ENST00000505888 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.123±0.00 N/A N/A
ENST00000506284 N/A N/A N/A N/A 0.227±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000507898 N/A N/A N/A N/A 0.017±0.00 N/A N/A N/A N/A N/A N/A N/A 0.277±0.00
ENST00000509417 N/A N/A 1.288±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000510854 0.073±0.00 0.102±0.00 N/A N/A 0.119±0.00 N/A N/A N/A N/A N/A N/A N/A 0.656±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006DX CIL_0006DX_0002 CGP 4:157076057-157366075
CIL_00007X CIL_00007X_0002 CGP 4:157204182-158173318

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004970 IDA:IEA ionotropic glutamate receptor activity
GO:0004971 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0008021 IEA synaptic vesicle
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0030666 TAS endocytic vesicle membrane
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IDA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052765 gria2b glutamate receptor, ionotropic, AMPA 2b protein_coding Danio_rerio
ENSDARG00000070173 gria2a glutamate receptor, ionotropic, AMPA 2a protein_coding Danio_rerio
ENSMUSG00000033981 Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) protein_coding Mus_musculus

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