C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 39
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137135 ARHGEF39 9606 - 9:35658875-35675866 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378387 ARHGEF39-001 35659344-35665287 protein_coding
  ENST00000468876 ARHGEF39-006 35662967-35664828 processed_transcript
  ENST00000475323 ARHGEF39-003 35658877-35665192 nonsense_mediated_decay
  ENST00000488918 ARHGEF39-005 35661838-35662644 processed_transcript
  ENST00000490638 ARHGEF39-004 35658875-35675866 nonsense_mediated_decay
  ENST00000490970 ARHGEF39-002 35661519-35665187 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378387ENST00000475323
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378387 0.948±0.00 0.735±0.00 N/A N/A N/A 0.257±0.00 N/A N/A N/A 0.049±0.00 N/A 2.794±2.18 0.947±0.00 1.361±0.05
ENST00000475323 3.997±0.00 3.491±0.00 0.020±0.00 1.348±0.65 11.515±0.00 10.231±0.00 3.188±0.00 1.642±1.58 2.247±0.00 4.548±0.00 3.132±2.57 3.740±0.51 3.095±1.05 3.489±0.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00072Q CIL_00072Q_0001 CGP 9:35649295-35661511
CIL_00072N CIL_00072N_0001 CGP 9:35658290-35675866
CIL_00072O CIL_00072O_0001 CGP 9:35658875-35681159

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005886 IDA plasma membrane
GO:0030335 IDA positive regulation of cell migration
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013476 arhgef39 Rho guanine nucleotide exchange factor (GEF) 39 protein_coding Danio_rerio
ENSMUSG00000051517 Arhgef39 Rho guanine nucleotide exchange factor (GEF) 39 protein_coding Mus_musculus

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