C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 39
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000051517 Arhgef39 10090 - 4:43496142-43499695 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054538 Arhgef39-001 43496142-43499695 protein_coding
  ENSMUST00000125834 Arhgef39-004 43496524-43499661 processed_transcript
  ENSMUST00000128754 Arhgef39-002 43496146-43499619 processed_transcript
  ENSMUST00000129378 Arhgef39-009 43496148-43497213 processed_transcript
  ENSMUST00000136005 Arhgef39-010 43496821-43499608 protein_coding
  ENSMUST00000146781 Arhgef39-005 43497732-43499611 processed_transcript
  ENSMUST00000147124 Arhgef39-007 43497261-43499075 processed_transcript
  ENSMUST00000152134 Arhgef39-008 43496142-43497234 protein_coding
  ENSMUST00000154905 Arhgef39-006 43497220-43499115 processed_transcript
  ENSMUST00000156058 Arhgef39-003 43499147-43499661 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054538ENSMUST00000125834ENSMUST00000128754ENSMUST00000129378ENSMUST00000146781ENSMUST00000147124ENSMUST00000152134ENSMUST00000154905
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054538 0.930±0.54 N/A 4.594±1.38 2.707±2.93 0.427±0.14 7.256±0.61 0.190±0.02 2.906±0.62 7.583±7.71 0.589±0.24 0.105±0.02 4.768±1.54 3.865±2.49 4.101±0.45
ENSMUST00000125834 1.009±0.75 0.882±0.32 2.741±1.15 4.272±2.66 0.385±0.15 11.138±2.75 0.219±0.05 3.037±1.04 5.970±6.12 0.663±0.39 0.171±0.00 4.650±1.78 1.534±1.02 2.708±1.27
ENSMUST00000128754 0.211±0.18 N/A 1.172±0.43 3.197±0.00 0.182±0.00 3.953±0.66 0.098±0.00 1.028±0.34 2.207±2.19 N/A 0.041±0.00 1.401±0.98 0.860±0.04 N/A
ENSMUST00000129378 N/A N/A N/A N/A 0.649±0.00 N/A N/A N/A N/A N/A 0.070±0.00 2.034±0.40 0.477±0.00 N/A
ENSMUST00000146781 N/A N/A N/A N/A N/A N/A N/A N/A 0.164±0.04 N/A 0.067±0.03 1.882±0.00 1.741±0.00 N/A
ENSMUST00000147124 N/A N/A N/A 0.154±0.00 N/A N/A N/A N/A N/A N/A 0.114±0.04 N/A N/A N/A
ENSMUST00000152134 N/A N/A N/A 0.067±0.00 N/A N/A 0.147±0.00 N/A N/A N/A 0.103±0.02 2.613±0.77 2.129±1.16 1.253±0.00
ENSMUST00000154905 N/A N/A N/A N/A N/A N/A N/A N/A 0.145±0.00 N/A N/A N/A N/A 0.648±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00072N CIL_00072N_0002 CGP 4:43492900-43499695
CIL_00072O CIL_00072O_0002 CGP 4:43496142-43513729

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005886 ISS plasma membrane
GO:0030335 ISS positive regulation of cell migration
GO:0032321 IEA positive regulation of Rho GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013476 arhgef39 Rho guanine nucleotide exchange factor (GEF) 39 protein_coding Danio_rerio
ENSG00000137135 ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39 protein_coding Homo_sapiens

Loading