C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aggrecan
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157766 ACAN 9606 + 15:88803443-88875354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000352105 ACAN-004 88803759-88874653 protein_coding
  ENST00000439576 ACAN-201 88803443-88875354 protein_coding
  ENST00000558207 ACAN-001 88803474-88851521 protein_coding
  ENST00000558604 ACAN-002 88873713-88874841 retained_intron
  ENST00000558704 ACAN-003 88872969-88874841 protein_coding
  ENST00000559004 ACAN-008 88803759-88874572 protein_coding
  ENST00000560601 ACAN-005 88859076-88871490 protein_coding
  ENST00000561243 ACAN-006 88836207-88874481 protein_coding
  ENST00000617301 ACAN-202 88803443-88875354 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000352105ENST00000439576ENST00000558207ENST00000558604ENST00000558704ENST00000559004ENST00000561243ENST00000617301
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000352105 N/A N/A N/A N/A 0.186±0.00 N/A 0.005±0.00 N/A N/A N/A 0.061±0.00 0.324±0.00 N/A N/A
ENST00000439576 N/A 0.189±0.00 N/A N/A N/A N/A N/A N/A N/A 0.472±0.00 N/A N/A 0.092±0.00 N/A
ENST00000558207 0.073±0.00 N/A N/A 0.133±0.00 0.041±0.00 0.063±0.00 0.075±0.00 N/A 0.031±0.00 N/A 0.098±0.06 N/A N/A N/A
ENST00000558604 N/A N/A N/A N/A 0.147±0.00 0.130±0.00 N/A 0.195±0.00 0.921±0.00 N/A N/A 1.406±0.00 1.090±0.00 N/A
ENST00000558704 N/A 1.700±0.00 1.014±0.00 0.474±0.00 N/A 0.467±0.00 N/A 0.214±0.00 N/A 3.909±0.00 0.364±0.00 N/A N/A 3.551±0.00
ENST00000559004 N/A N/A N/A N/A 0.068±0.00 N/A 0.001±0.00 N/A N/A N/A 0.071±0.00 N/A 0.200±0.00 N/A
ENST00000561243 0.040±0.00 N/A N/A 0.051±0.00 N/A N/A 0.002±0.00 N/A N/A 0.405±0.00 0.117±0.00 0.088±0.00 0.099±0.00 N/A
ENST00000617301 0.042±0.00 0.558±0.00 0.110±0.00 0.191±0.00 0.019±0.00 0.175±0.00 N/A 1.261±0.00 0.186±0.00 0.677±0.00 N/A 0.732±0.40 0.253±0.12 0.816±0.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011K CIL_00011K_0001 CGP 15:88636153-88875354
CIL_00011L CIL_00011L_0001 CGP 15:88803443-88895626

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001502 IEA cartilage condensation
GO:0002063 IEA chondrocyte development
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005540 IEA hyaluronic acid binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005604 IEA basement membrane
GO:0007155 IEA cell adhesion
GO:0030166 IEA proteoglycan biosynthetic process
GO:0030199 IEA collagen fibril organization
GO:0030246 IEA carbohydrate binding
GO:0031012 IEA extracellular matrix

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035891 acana aggrecan a protein_coding Danio_rerio
ENSDARG00000045799 acanb aggrecan b protein_coding Danio_rerio
ENSMUSG00000030607 Acan aggrecan protein_coding Mus_musculus

Loading