C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 22 (organic cation/carnitine transporter), member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197375 SLC22A5 9606 + 5:132369752-132395614 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000245407 SLC22A5-001 132369752-132395614 protein_coding
  ENST00000415928 SLC22A5-004 132370276-132387151 protein_coding
  ENST00000435065 SLC22A5-201 132369973-132394272 protein_coding
  ENST00000437841 SLC22A5-008 132369900-132389005 nonsense_mediated_decay
  ENST00000447841 SLC22A5-005 132388911-132394752 nonsense_mediated_decay
  ENST00000448810 SLC22A5-002 132385328-132393815 nonsense_mediated_decay
  ENST00000461013 SLC22A5-006 132376086-132395611 retained_intron
  ENST00000475308 SLC22A5-003 132388960-132395613 retained_intron
  ENST00000479605 SLC22A5-007 132387813-132393683 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245407ENST00000448810ENST00000461013ENST00000475308
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245407 0.701±0.00 N/A N/A 1.603±0.00 4.716±0.00 2.049±0.91 3.388±0.00 32.853±0.00 0.984±0.00 2.191±0.00 14.866±0.00 2.191±1.77 3.331±0.48 2.867±1.03
ENST00000448810 N/A N/A N/A N/A N/A N/A N/A 2.504±0.00 N/A N/A N/A N/A N/A N/A
ENST00000461013 N/A N/A 1.790±0.00 0.290±0.00 0.551±0.00 0.202±0.00 0.268±0.15 N/A 0.189±0.08 N/A N/A N/A 0.185±0.00 N/A
ENST00000475308 N/A 1.021±0.00 N/A N/A 0.614±0.00 N/A N/A N/A N/A 1.275±0.00 N/A N/A N/A 0.908±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093D CIL_00093D_0001 VISTA 5:131965137-132566411
CIL_0007RF CIL_0007RF_0001 VISTA 5:131967147-132570227
CIL_0000HR CIL_0000HR_0002 CGP 5:132294443-132395614

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IC plasma membrane
GO:0006814 IEA sodium ion transport
GO:0006855 IC drug transmembrane transport
GO:0015075 IEA ion transmembrane transporter activity
GO:0015226 IDA carnitine transmembrane transporter activity
GO:0015238 IC drug transmembrane transporter activity
GO:0015293 IEA symporter activity
GO:0015651 IDA quaternary ammonium group transmembrane transporter activity
GO:0015697 IDA quaternary ammonium group transport
GO:0015879 IDA carnitine transport
GO:0015893 IC drug transport
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0022857 IEA transmembrane transporter activity
GO:0030165 IPI PDZ domain binding
GO:0031526 IDA brush border membrane
GO:0034220 IEA ion transmembrane transport
GO:0042891 IEA antibiotic transport
GO:0042895 IEA antibiotic transporter activity
GO:0052106 IMP quorum sensing involved in interaction with host
GO:0055085 TAS:IEA transmembrane transport
GO:0060731 IMP positive regulation of intestinal epithelial structure maintenance
GO:0070062 IDA extracellular vesicular exosome
GO:0070715 IDA sodium-dependent organic cation transport
GO:1902603 IDA carnitine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005335 slc22a4 solute carrier family 22 (organic cation/ergothioneine transporter), member 4 protein_coding Danio_rerio
ENSDARG00000068603 slc22a5 solute carrier family 22 (organic cation/carnitine transporter), member 5 protein_coding Danio_rerio
ENSDARG00000094112 slc22a21 solute carrier family 22 (organic cation transporter), member 21 protein_coding Danio_rerio
ENSMUSG00000018900 Slc22a5 solute carrier family 22 (organic cation transporter), member 5 protein_coding Mus_musculus
ENSMUSG00000063652 Slc22a21 solute carrier family 22 (organic cation transporter), member 21 protein_coding Mus_musculus

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