C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 22 (organic cation/carnitine transporter), member 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000245407 SLC22A5-001 ENSG00000197375 9606 + 5:132369752-132395614 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245407
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245407 0.701±0.00 1.603±0.00 4.716±0.00 2.049±0.91 3.388±0.00 32.853±0.00 0.984±0.00 2.191±0.00 14.866±0.00 2.191±1.77 3.331±0.48 2.867±1.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093D CIL_00093D_0001 VISTA 5:131965137-132566411
CIL_0007RF CIL_0007RF_0001 VISTA 5:131967147-132570227
CIL_0000HR CIL_0000HR_0002 CGP 5:132294443-132395614

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IC plasma membrane
GO:0006814 IEA sodium ion transport
GO:0006855 IC drug transmembrane transport
GO:0015075 IEA ion transmembrane transporter activity
GO:0015226 IDA carnitine transmembrane transporter activity
GO:0015238 IC drug transmembrane transporter activity
GO:0015293 IEA symporter activity
GO:0015651 IDA quaternary ammonium group transmembrane transporter activity
GO:0015697 IDA quaternary ammonium group transport
GO:0015879 IDA carnitine transport
GO:0015893 IC drug transport
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0022857 IEA transmembrane transporter activity
GO:0030165 IPI PDZ domain binding
GO:0031526 IDA brush border membrane
GO:0034220 IEA ion transmembrane transport
GO:0042891 IEA antibiotic transport
GO:0042895 IEA antibiotic transporter activity
GO:0052106 IMP quorum sensing involved in interaction with host
GO:0055085 TAS:IEA transmembrane transport
GO:0060731 IMP positive regulation of intestinal epithelial structure maintenance
GO:0070062 IDA extracellular vesicular exosome
GO:0070715 IDA sodium-dependent organic cation transport
GO:1902603 IDA carnitine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000019044 Slc22a5-001 protein_coding Mus_musculus 0 1901
ENSMUST00000076493 Slc22a21-001 protein_coding Mus_musculus 0 1476
ENSMUST00000020586 Slc22a4-001 protein_coding Mus_musculus 0 798
ENSMUST00000124221 Slc22a21-003 nonsense_mediated_decay Mus_musculus 0 544
ENSMUST00000152084 Slc22a5-003 nonsense_mediated_decay Mus_musculus 0 466
ENSMUST00000136307 Slc22a5-002 nonsense_mediated_decay Mus_musculus 0 460
ENSMUST00000154369 Slc22a4-003 processed_transcript Mus_musculus 0 366

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