C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000008855 Hdac5 10090 - 11:102194432-102230166 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000008999 Hdac5-002 102195744-102230124 protein_coding
  ENSMUST00000107150 Hdac5-019 102195751-102230136 protein_coding
  ENSMUST00000107151 Hdac5-003 102194432-102230166 protein_coding
  ENSMUST00000107152 Hdac5-001 102195751-102230166 protein_coding
  ENSMUST00000124077 Hdac5-007 102195749-102230139 nonsense_mediated_decay
  ENSMUST00000125072 Hdac5-004 102219153-102230146 processed_transcript
  ENSMUST00000126453 Hdac5-011 102198964-102200357 retained_intron
  ENSMUST00000128686 Hdac5-006 102218711-102230133 processed_transcript
  ENSMUST00000131254 Hdac5-009 102206628-102218928 protein_coding
  ENSMUST00000133651 Hdac5-010 102199390-102200816 retained_intron
  ENSMUST00000136304 Hdac5-015 102195747-102197185 retained_intron
  ENSMUST00000137787 Hdac5-014 102196237-102198079 retained_intron
  ENSMUST00000140481 Hdac5-013 102196681-102198895 retained_intron
  ENSMUST00000140962 Hdac5-018 102195749-102196568 protein_coding
  ENSMUST00000145540 Hdac5-017 102195749-102196558 retained_intron
  ENSMUST00000149087 Hdac5-020 102195749-102218929 retained_intron
  ENSMUST00000150683 Hdac5-008 102207031-102218929 retained_intron
  ENSMUST00000150965 Hdac5-021 102195749-102197868 retained_intron
  ENSMUST00000155065 Hdac5-012 102198679-102199493 retained_intron
  ENSMUST00000156337 Hdac5-005 102205887-102230142 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107150ENSMUST00000107151ENSMUST00000107152ENSMUST00000124077ENSMUST00000126453ENSMUST00000133651ENSMUST00000137787ENSMUST00000140481ENSMUST00000140962ENSMUST00000149087ENSMUST00000150965
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107150 6.520±0.56 8.010±2.88 5.366±0.13 10.942±1.20 12.294±3.45 9.671±0.98 6.696±1.04 5.366±0.38 2.548±1.05 13.428±2.05 5.343±1.15 8.901±2.55 3.383±1.96 N/A
ENSMUST00000107151 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.278±0.00
ENSMUST00000107152 11.973±0.51 12.401±3.30 13.598±2.84 17.841±0.99 15.697±1.48 12.628±3.19 8.582±1.43 7.958±2.18 5.843±2.77 19.046±1.71 6.817±1.99 13.743±4.23 6.740±5.09 3.555±0.72
ENSMUST00000124077 4.332±0.26 4.575±0.81 N/A 12.231±0.00 N/A N/A 3.767±0.08 3.598±0.63 0.877±0.00 5.859±0.00 5.832±1.29 6.209±1.85 4.851±2.42 2.422±0.50
ENSMUST00000126453 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.340±0.00 N/A
ENSMUST00000133651 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.875±0.00 N/A
ENSMUST00000137787 N/A N/A N/A N/A 6.498±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000140481 N/A N/A N/A 39.588±0.00 5.926±0.00 N/A N/A N/A N/A N/A N/A 22.061±0.00 7.677±3.97 4.368±0.00
ENSMUST00000140962 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 23.439±0.00 11.590±0.00
ENSMUST00000149087 N/A N/A N/A N/A 1.471±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000150965 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 25.759±8.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B6 CIL_0009B6_0002 VISTA 11:102063033-102664797
CIL_0005J5 CIL_0005J5_0002 CGP 11:102189620-102230166
CIL_0005J4 CIL_0005J4_0002 CGP 11:102194432-102265187

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001047 IEA core promoter binding
GO:0002076 IMP osteoblast development
GO:0003714 IDA transcription corepressor activity
GO:0004407 IEA histone deacetylase activity
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 IDA cytosol
GO:0007507 IGI heart development
GO:0008134 IEA transcription factor binding
GO:0010832 IEA negative regulation of myotube differentiation
GO:0016575 IEA histone deacetylation
GO:0016604 IDA nuclear body
GO:0033555 IMP multicellular organismal response to stress
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0042220 IDA response to cocaine
GO:0042493 IEA response to drug
GO:0043234 IEA protein complex
GO:0043393 IEA regulation of protein binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045668 IMP negative regulation of osteoblast differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048742 IGI regulation of skeletal muscle fiber development
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051153 IGI regulation of striated muscle cell differentiation
GO:0070491 IEA repressing transcription factor binding
GO:0090051 IEA negative regulation of cell migration involved in sprouting angiogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075139 hdac5 histone deacetylase 5 protein_coding Danio_rerio
ENSG00000108840 HDAC5 histone deacetylase 5 protein_coding Homo_sapiens

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