C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020719 Ddx5 10090 - 11:106780355-106789185 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021062 Ddx5-001 106780355-106788532 protein_coding
  ENSMUST00000106778 Ddx5-006 106783733-106785046 retained_intron
  ENSMUST00000106779 Ddx5-008 106783312-106788467 processed_transcript
  ENSMUST00000123339 Ddx5-004 106786071-106788883 protein_coding
  ENSMUST00000127481 Ddx5-007 106781976-106788488 nonsense_mediated_decay
  ENSMUST00000129585 Ddx5-003 106785496-106789185 protein_coding
  ENSMUST00000130172 Ddx5-009 106782114-106783651 processed_transcript
  ENSMUST00000133426 Ddx5-002 106781548-106788494 nonsense_mediated_decay
  ENSMUST00000151741 Ddx5-005 106785143-106786050 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021062ENSMUST00000106778ENSMUST00000127481ENSMUST00000129585ENSMUST00000130172ENSMUST00000133426
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021062 40.558±14.35 N/A 73.258±8.14 150.317±65.35 38.952±1.81 31.452±5.67 23.242±1.28 41.094±8.16 41.881±17.43 69.738±13.34 40.552±3.58 91.701±57.44 79.591±32.90 73.549±39.87
ENSMUST00000106778 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 309.197±0.00 164.031±43.85 646.532±0.00
ENSMUST00000127481 N/A 2798.367±70.51 N/A N/A 405.435±180.25 350.018±71.70 N/A 70.559±3.98 157.617±33.47 311.029±119.68 N/A 774.687±452.27 N/A N/A
ENSMUST00000129585 N/A 205.890±15.54 N/A N/A 104.606±15.28 68.845±14.54 N/A 46.580±0.00 27.205±4.71 N/A N/A 124.788±17.31 N/A 228.920±25.91
ENSMUST00000130172 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 676.513±0.00 442.630±55.97 2051.430±0.00
ENSMUST00000133426 106.555±11.37 N/A 203.310±24.11 125.591±30.91 91.521±12.65 50.335±6.45 67.900±6.11 57.667±4.58 50.789±20.24 143.788±20.95 78.905±10.68 97.818±51.14 62.454±22.31 63.059±3.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012I CIL_00012I_0002 CGP 11:106768253-106789185
CIL_00012F CIL_00012F_0002 CGP 11:106780355-106819930

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000381 IEA regulation of alternative mRNA splicing, via spliceosome
GO:0001701 IMP in utero embryonic development
GO:0003676 IEA nucleic acid binding
GO:0003712 IDA transcription cofactor activity
GO:0003713 IEA transcription coactivator activity
GO:0004004 IEA ATP-dependent RNA helicase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IC nucleus
GO:0005730 IEA nucleolus
GO:0006200 IEA ATP catabolic process
GO:0007623 IMP circadian rhythm
GO:0008026 IEA ATP-dependent helicase activity
GO:0016020 IEA membrane
GO:0019899 IEA enzyme binding
GO:0030331 IEA estrogen receptor binding
GO:0030529 ISO ribonucleoprotein complex
GO:0033148 IEA positive regulation of intracellular estrogen receptor signaling pathway
GO:0036002 IEA pre-mRNA binding
GO:0043517 IEA positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044822 IEA poly(A) RNA binding
GO:0045069 IEA regulation of viral genome replication
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048306 IEA calcium-dependent protein binding
GO:0050681 IEA androgen receptor binding
GO:0060765 IEA regulation of androgen receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome
GO:0071013 IEA catalytic step 2 spliceosome
GO:0072332 IEA intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038068 ddx5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 protein_coding Danio_rerio
ENSG00000108654 DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 protein_coding Homo_sapiens

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