C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DEAD (Asp-Glu-Ala-Asp) box helicase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108654 DDX5 9606 - 17:64499616-64508199 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000225792 DDX5-001 64499616-64506521 protein_coding
  ENST00000450599 DDX5-006 64499622-64506287 protein_coding
  ENST00000540698 DDX5-003 64499616-64506289 nonsense_mediated_decay
  ENST00000577787 DDX5-019 64502585-64503823 protein_coding
  ENST00000577922 DDX5-010 64503441-64506731 protein_coding
  ENST00000578190 DDX5-027 64503856-64505390 protein_coding
  ENST00000578400 DDX5-028 64503095-64506323 nonsense_mediated_decay
  ENST00000578491 DDX5-023 64500824-64503096 processed_transcript
  ENST00000578758 DDX5-030 64500134-64502350 retained_intron
  ENST00000578804 DDX5-005 64499914-64505956 protein_coding
  ENST00000579091 DDX5-014 64504015-64505451 protein_coding
  ENST00000579461 DDX5-029 64501876-64503246 retained_intron
  ENST00000579996 DDX5-007 64502070-64503435 protein_coding
  ENST00000580026 DDX5-031 64500110-64501902 processed_transcript
  ENST00000581230 DDX5-002 64499616-64506289 retained_intron
  ENST00000581237 DDX5-032 64500185-64501697 processed_transcript
  ENST00000581551 DDX5-022 64502900-64503561 retained_intron
  ENST00000581693 DDX5-004 64499616-64506289 nonsense_mediated_decay
  ENST00000581697 DDX5-012 64503568-64506626 protein_coding
  ENST00000581806 DDX5-009 64503839-64506903 protein_coding
  ENST00000582326 DDX5-020 64502930-64503684 retained_intron
  ENST00000583201 DDX5-021 64502921-64503646 retained_intron
  ENST00000583212 DDX5-015 64504078-64505281 protein_coding
  ENST00000583239 DDX5-013 64503995-64505527 protein_coding
  ENST00000583562 DDX5-016 64503720-64504289 retained_intron
  ENST00000583699 DDX5-033 64506800-64507712 processed_transcript
  ENST00000583894 DDX5-017 64502965-64504021 retained_intron
  ENST00000584279 DDX5-011 64504064-64506686 protein_coding
  ENST00000584500 DDX5-034 64506927-64508199 processed_transcript
  ENST00000584549 DDX5-018 64502730-64503848 retained_intron
  ENST00000585060 DDX5-026 64504060-64506289 protein_coding
  ENST00000585111 DDX5-008 64504755-64507530 protein_coding
  ENST00000585223 DDX5-025 64504358-64506289 retained_intron
  ENST00000585317 DDX5-024 64501888-64502902 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000225792ENST00000450599ENST00000540698ENST00000578491ENST00000578804ENST00000581230ENST00000581237ENST00000581693
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000225792 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.646±0.00 69.911±15.10 74.195±7.15 N/A
ENST00000450599 34.141±0.00 N/A N/A N/A 39.118±0.00 14.663±0.00 N/A 39.724±0.00 16.887±0.00 47.169±0.00 7.023±0.00 N/A 25.788±0.00 70.720±0.00
ENST00000540698 N/A N/A N/A 23.594±0.00 N/A N/A 15.985±0.00 15.085±0.00 33.637±0.00 N/A 14.418±0.00 61.118±24.00 52.246±0.00 95.930±0.00
ENST00000578491 N/A N/A 153.057±0.00 112.221±0.00 275.658±0.00 N/A N/A 70.115±0.00 167.545±0.00 N/A N/A 153.275±0.00 N/A N/A
ENST00000578804 30.249±0.00 N/A N/A 28.014±0.00 N/A N/A N/A N/A N/A N/A 6.592±0.00 N/A N/A N/A
ENST00000581230 16.412±0.00 75.224±0.00 31.911±0.00 21.899±1.17 44.467±10.86 47.586±33.20 18.413±4.28 31.607±17.61 20.476±9.62 89.461±41.75 6.826±0.00 40.825±12.17 12.154±0.00 87.150±0.00
ENST00000581237 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 282.078±0.00 144.067±0.00 429.166±0.00
ENST00000581693 48.360±0.00 105.814±0.00 N/A 28.163±0.00 43.931±0.00 13.891±0.00 28.734±0.00 52.218±0.00 28.822±0.00 61.091±0.00 12.026±0.00 55.792±0.00 N/A 84.168±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012I CIL_00012I_0001 CGP 17:64477785-64508199
CIL_00012F CIL_00012F_0001 CGP 17:64499616-64542461

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000381 IDA regulation of alternative mRNA splicing, via spliceosome
GO:0000398 IC mRNA splicing, via spliceosome
GO:0001701 IEA in utero embryonic development
GO:0003676 IEA nucleic acid binding
GO:0003712 IEA transcription cofactor activity
GO:0003713 IDA transcription coactivator activity
GO:0003724 NAS:IEA RNA helicase activity
GO:0004004 IEA ATP-dependent RNA helicase activity
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IDA:IEA nucleus
GO:0005730 IDA nucleolus
GO:0006200 IEA ATP catabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0007623 IEA circadian rhythm
GO:0008026 IEA ATP-dependent helicase activity
GO:0016020 IDA membrane
GO:0016049 NAS cell growth
GO:0016818 IEA hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0019899 IEA enzyme binding
GO:0030331 IDA estrogen receptor binding
GO:0030529 IDA ribonucleoprotein complex
GO:0033148 IDA positive regulation of intracellular estrogen receptor signaling pathway
GO:0036002 IDA pre-mRNA binding
GO:0043517 IMP positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044822 IDA poly(A) RNA binding
GO:0045069 IEA regulation of viral genome replication
GO:0045667 ISS regulation of osteoblast differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048306 IEA calcium-dependent protein binding
GO:0050681 IDA androgen receptor binding
GO:0060765 IMP regulation of androgen receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071013 IDA catalytic step 2 spliceosome
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator
GO:2001014 ISS regulation of skeletal muscle cell differentiation
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038068 ddx5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 protein_coding Danio_rerio
ENSMUSG00000020719 Ddx5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 protein_coding Mus_musculus

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