C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, alpha type 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000060073 Psma3 10090 + 12:70974621-70996347 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071704 Psma3-005 70974715-70994475 nonsense_mediated_decay
  ENSMUST00000160027 Psma3-001 70974621-70996347 protein_coding
  ENSMUST00000160683 Psma3-004 70974671-70994501 retained_intron
  ENSMUST00000160864 Psma3-007 70974683-70994505 protein_coding
  ENSMUST00000161041 Psma3-003 70974708-70979694 retained_intron
  ENSMUST00000162626 Psma3-002 70974671-70994921 nonsense_mediated_decay
  ENSMUST00000162851 Psma3-008 70974689-70994504 nonsense_mediated_decay
  ENSMUST00000162898 Psma3-009 70986892-70994505 protein_coding
  ENSMUST00000163035 Psma3-006 70974719-70984837 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071704ENSMUST00000160027ENSMUST00000160683ENSMUST00000160864ENSMUST00000162851
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071704 27.279±7.17 52.886±10.29 44.762±1.06 21.684±7.46 43.093±8.40 28.855±7.36 9.349±3.85 27.585±7.82 62.697±9.63 32.115±5.32 37.819±7.37 44.551±17.15 43.929±16.81 27.268±8.55
ENSMUST00000160027 2.874±1.03 2.589±0.41 N/A 8.921±3.98 3.178±0.00 2.028±0.48 1.546±0.16 3.110±0.23 3.783±0.44 2.696±0.14 6.595±0.48 2.866±0.52 N/A N/A
ENSMUST00000160683 9.471±1.76 13.471±1.67 58.923±5.95 22.284±14.00 12.979±4.39 7.797±2.63 9.425±0.83 11.315±2.63 32.644±23.00 12.976±2.39 26.470±3.31 18.275±6.59 39.843±16.24 15.566±2.70
ENSMUST00000160864 17.624±4.26 N/A 42.154±0.56 23.155±0.00 91.573±26.01 N/A 16.414±8.79 14.137±6.03 58.635±11.33 13.514±0.16 30.224±6.97 69.519±11.64 54.009±16.56 15.812±0.00
ENSMUST00000162851 N/A N/A N/A 129.496±0.00 N/A N/A N/A N/A N/A N/A N/A 219.693±0.00 377.487±217.88 161.616±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001K7 CIL_0001K7_0002 CGP 12:70937857-70996347
CIL_0004LX CIL_0004LX_0002 CGP 12:70974621-71098592

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 IEA proteasome complex
GO:0004175 IEA endopeptidase activity
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0005839 IDA proteasome core complex
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0019773 IEA proteasome core complex, alpha-subunit complex
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086618 psma3 proteasome (prosome, macropain) subunit, alpha type, 3 protein_coding Danio_rerio
ENSG00000100567 PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 protein_coding Homo_sapiens

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