C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histocompatibility 2, class II antigen A, beta 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000040828 H2-Ab1-001 ENSMUSG00000073421 10090 + 17:34263209-34269418 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040828
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040828 373.476±71.29 183.337±36.10 112.444±10.45 0.486±0.14 993.054±243.86 272.781±30.79 57.580±22.40 164.666±22.41 24.777±22.17 504.754±132.77 14.563±14.74 287.639±119.84 5.713±9.57 11.183±5.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PK CIL_0001PK_0006 CGP 17:34238903-34269418
CIL_0002XS CIL_0002XS_0009 CGP 17:34263209-34287827

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002344 IDA B cell affinity maturation
GO:0002579 IDA positive regulation of antigen processing and presentation
GO:0002827 IDA positive regulation of T-helper 1 type immune response
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005769 IDA early endosome
GO:0005771 IDA multivesicular body
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006955 IMP immune response
GO:0008134 IDA transcription factor binding
GO:0009897 IDA external side of plasma membrane
GO:0015643 IPI toxic substance binding
GO:0016021 IDA integral component of membrane
GO:0019882 IDA antigen processing and presentation
GO:0019886 IDA antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0031625 IPI ubiquitin protein ligase binding
GO:0042605 IDA peptide antigen binding
GO:0042613 IDA MHC class II protein complex
GO:0046635 IDA positive regulation of alpha-beta T cell activation
GO:0048002 IDA antigen processing and presentation of peptide antigen
GO:0070491 IPI repressing transcription factor binding
GO:0071346 IDA cellular response to interferon-gamma

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000323109 HLA-DQB2-001 protein_coding Homo_sapiens 0 580
ENST00000374943 HLA-DQB1-002 protein_coding Homo_sapiens 0 638
ENST00000383121 HLA-DQB1-001 protein_coding Homo_sapiens 0 614
ENST00000383247 HLA-DQB1-001 protein_coding Homo_sapiens 0 614
ENST00000399065 HLA-DQB1-002 protein_coding Homo_sapiens 0 682
ENST00000399074 HLA-DQB1-002 protein_coding Homo_sapiens 0 682
ENST00000399079 HLA-DQB1-004 protein_coding Homo_sapiens 0 477
ENST00000399082 HLA-DQB1-007 protein_coding Homo_sapiens 0 274
ENST00000399084 HLA-DQB1-003 protein_coding Homo_sapiens 0 592
ENST00000399088 HLA-DQB1-001 protein_coding Homo_sapiens 0 630
ENST00000399658 HLA-DQB2-002 protein_coding Homo_sapiens 0 444
ENST00000399661 HLA-DQB2-003 protein_coding Homo_sapiens 0 599
ENST00000399670 HLA-DQB1-051 protein_coding Homo_sapiens 0 494
ENST00000411527 HLA-DQB2-002 protein_coding Homo_sapiens 0 444
ENST00000413089 HLA-DQB1-003 protein_coding Homo_sapiens 0 630
ENST00000414518 HLA-DQB1-001 protein_coding Homo_sapiens 0 625
ENST00000415137 HLA-DQB2-001 protein_coding Homo_sapiens 0 608
ENST00000415926 HLA-DQB1-004 protein_coding Homo_sapiens 0 499
ENST00000416131 HLA-DQB2-004 protein_coding Homo_sapiens 0 444
ENST00000416192 HLA-DQB1-001 protein_coding Homo_sapiens 0 630
ENST00000417780 HLA-DQB2-002 protein_coding Homo_sapiens 0 444
ENST00000418419 HLA-DQB2-004 protein_coding Homo_sapiens 0 449
ENST00000419109 HLA-DQB2-004 protein_coding Homo_sapiens 0 444
ENST00000419519 HLA-DQB2-001 protein_coding Homo_sapiens 0 580
ENST00000419685 HLA-DQB2-003 protein_coding Homo_sapiens 0 627
ENST00000419914 HLA-DQB1-001 protein_coding Homo_sapiens 0 619
ENST00000421468 HLA-DQB2-004 protein_coding Homo_sapiens 0 449
ENST00000421888 HLA-DQB1-002 protein_coding Homo_sapiens 0 671
ENST00000422950 HLA-DQB1-003 protein_coding Homo_sapiens 0 630
ENST00000424530 HLA-DQB1-004 protein_coding Homo_sapiens 0 516
ENST00000424579 HLA-DQB2-004 protein_coding Homo_sapiens 0 444
ENST00000424806 HLA-DQB1-003 protein_coding Homo_sapiens 0 619
ENST00000426733 HLA-DQB2-002 protein_coding Homo_sapiens 0 444
ENST00000427449 HLA-DQB2-004 protein_coding Homo_sapiens 0 444
ENST00000428219 HLA-DQB1-007 protein_coding Homo_sapiens 0 302
ENST00000428972 HLA-DQB2-002 protein_coding Homo_sapiens 0 444
ENST00000429783 HLA-DQB2-003 protein_coding Homo_sapiens 0 627
ENST00000430668 HLA-DQB2-003 protein_coding Homo_sapiens 0 621
ENST00000430790 HLA-DQB1-007 protein_coding Homo_sapiens 0 279
ENST00000430849 HLA-DQB2-003 protein_coding Homo_sapiens 0 599
ENST00000432486 HLA-DQB2-003 protein_coding Homo_sapiens 0 599
ENST00000432856 HLA-DQB1-006 protein_coding Homo_sapiens 0 329
ENST00000433114 HLA-DQB2-002 protein_coding Homo_sapiens 0 444
ENST00000433801 HLA-DQB2-001 protein_coding Homo_sapiens 0 580
ENST00000433936 HLA-DQB1-007 protein_coding Homo_sapiens 0 274
ENST00000434651 HLA-DQB1-001 protein_coding Homo_sapiens 0 592
ENST00000434886 HLA-DQB1-004 protein_coding Homo_sapiens 0 510
ENST00000435081 HLA-DQB2-004 protein_coding Homo_sapiens 0 444
ENST00000435145 HLA-DQB2-001 protein_coding Homo_sapiens 0 603
ENST00000437316 HLA-DQB2-003 protein_coding Homo_sapiens 0 621
ENST00000438757 HLA-DQB2-002 protein_coding Homo_sapiens 0 449
ENST00000442043 HLA-DQB2-001 protein_coding Homo_sapiens 0 580
ENST00000442806 HLA-DQB2-001 protein_coding Homo_sapiens 0 603
ENST00000447979 HLA-DQB2-004 protein_coding Homo_sapiens 0 444
ENST00000455520 HLA-DQB2-001 protein_coding Homo_sapiens 0 608
ENST00000456529 HLA-DQB2-002 protein_coding Homo_sapiens 0 449
ENST00000456954 HLA-DQB1-006 protein_coding Homo_sapiens 0 324
ENST00000457432 HLA-DQB2-003 protein_coding Homo_sapiens 0 599
ENST00000457445 HLA-DQB1-006 protein_coding Homo_sapiens 0 318
ENST00000472708 HLA-DQB1-005 retained_intron Homo_sapiens 0 274
ENST00000475182 HLA-DQB1-005 retained_intron Homo_sapiens 0 302
ENST00000479570 HLA-DQB1-005 retained_intron Homo_sapiens 0 279
ENST00000484729 HLA-DQB1-008 nonsense_mediated_decay Homo_sapiens 0 267
ENST00000487676 HLA-DQB1-005 retained_intron Homo_sapiens 0 274

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