C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: profilin 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000066882 Pfn2-001 ENSMUSG00000027805 10090 - 3:57841895-57847564 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066882
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066882 14.856±9.98 23.866±1.74 40.447±7.72 176.007±50.89 8.344±3.84 3.133±0.64 18.078±1.27 25.112±2.08 1.820±0.97 7.443±1.48 78.004±6.32 22.770±5.67 6.050±3.40 54.690±19.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002R5 CIL_0002R5_0002 CGP 3:57736066-57847564
CIL_0002QZ CIL_0002QZ_0002 CGP 3:57841895-58466787

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000774 IEA adenyl-nucleotide exchange factor activity
GO:0003785 IEA actin monomer binding
GO:0005515 IPI protein binding
GO:0005546 IEA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0010633 IMP negative regulation of epithelial cell migration
GO:0030036 IEA actin cytoskeleton organization
GO:0030837 IDA negative regulation of actin filament polymerization
GO:0030838 IMP positive regulation of actin filament polymerization
GO:0032233 IEA positive regulation of actin filament bundle assembly
GO:0032781 IEA positive regulation of ATPase activity
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0043195 IDA terminal bouton
GO:0051496 IMP positive regulation of stress fiber assembly
GO:0070062 IEA extracellular vesicular exosome
GO:1900028 IMP negative regulation of ruffle assembly
GO:2000300 IMP regulation of synaptic vesicle exocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000153678 pfn2l-003 protein_coding Danio_rerio 0 311
ENSDART00000053426 pfn2l-001 protein_coding Danio_rerio 0 311
ENST00000239940 PFN2-001 protein_coding Homo_sapiens 0 1133
ENST00000423691 PFN2-003 protein_coding Homo_sapiens 0 632
ENST00000452853 PFN2-002 protein_coding Homo_sapiens 0 1133
ENST00000460404 PFN2-004 nonsense_mediated_decay Homo_sapiens 0 571
ENST00000461868 PFN2-009 protein_coding Homo_sapiens 0 617
ENST00000461930 PFN2-011 protein_coding Homo_sapiens 0 542
ENST00000468323 PFN2-012 nonsense_mediated_decay Homo_sapiens 0 438
ENST00000475518 PFN2-015 protein_coding Homo_sapiens 0 579
ENST00000481275 PFN2-016 protein_coding Homo_sapiens 0 579
ENST00000481767 PFN2-006 protein_coding Homo_sapiens 0 1075
ENST00000489155 PFN2-007 protein_coding Homo_sapiens 0 579
ENST00000490975 PFN2-010 protein_coding Homo_sapiens 0 553
ENST00000494827 PFN2-019 protein_coding Homo_sapiens 0 311
ENST00000497060 PFN2-017 retained_intron Homo_sapiens 0 303
ENST00000497148 PFN2-018 protein_coding Homo_sapiens 0 579
ENST00000498169 PFN2-013 nonsense_mediated_decay Homo_sapiens 0 686
ENST00000498307 PFN2-008 protein_coding Homo_sapiens 0 580

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