C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: profilin 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000239940 PFN2-001 ENSG00000070087 9606 - 3:149964904-149971109 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000239940
Transcript ID Adrenal Brain Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000239940 3.900±0.00 66.812±40.77 6.587±2.54 12.312±0.00 17.896±0.00 5.513±0.00 26.126±20.26 12.282±3.98 11.866±0.00 10.825±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002R7 CIL_0002R7_0001 CGP 3:149738470-149968385
CIL_0002R6 CIL_0002R6_0001 CGP 3:149761105-149968385
CIL_0002R5 CIL_0002R5_0001 CGP 3:149812708-150050788
CIL_0002QZ CIL_0002QZ_0001 CGP 3:149964904-150466431

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000774 IDA adenyl-nucleotide exchange factor activity
GO:0003779 IEA actin binding
GO:0003785 IPI actin monomer binding
GO:0005515 IPI protein binding
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0010633 IMP negative regulation of epithelial cell migration
GO:0030036 IEA actin cytoskeleton organization
GO:0030837 IDA negative regulation of actin filament polymerization
GO:0030838 IGI positive regulation of actin filament polymerization
GO:0032233 IMP positive regulation of actin filament bundle assembly
GO:0032781 IDA positive regulation of ATPase activity
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0043195 IEA terminal bouton
GO:0051496 IMP positive regulation of stress fiber assembly
GO:0070062 IDA extracellular vesicular exosome
GO:1900028 IMP negative regulation of ruffle assembly
GO:2000300 IEA regulation of synaptic vesicle exocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066882 Pfn2-001 protein_coding Mus_musculus 0 1133
ENSMUST00000119344 Pfn2-002 protein_coding Mus_musculus 0 1127
ENSMUST00000122210 Pfn2-004 protein_coding Mus_musculus 0 579
ENSMUST00000120289 Pfn2-003 protein_coding Mus_musculus 0 525
ENSDART00000153678 pfn2l-003 protein_coding Danio_rerio 0 327
ENSDART00000053426 pfn2l-001 protein_coding Danio_rerio 0 327

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