C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: vascular endothelial growth factor A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000071648 Vegfa-001 ENSMUSG00000023951 10090 - 17:46016993-46032369 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071648
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071648 18.042±3.96 59.481±28.46 16.509±4.82 19.225±5.45 15.337±2.48 16.681±2.58 26.629±6.43 17.426±4.37 15.012±7.20 87.723±16.13 24.305±2.04 22.007±7.28 12.379±8.12 0.724±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YI CIL_0008YI_0002 VISTA 17:45708824-46310190
CIL_00049T CIL_00049T_0002 CGP 17:46016993-46128910

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IDA angiogenesis
GO:0001541 IMP ovarian follicle development
GO:0001568 IMP blood vessel development
GO:0001569 IMP patterning of blood vessels
GO:0001701 IMP in utero embryonic development
GO:0001822 IMP kidney development
GO:0001938 ISO positive regulation of endothelial cell proliferation
GO:0001944 IMP vasculature development
GO:0002052 IGI positive regulation of neuroblast proliferation
GO:0002053 IDA positive regulation of mesenchymal cell proliferation
GO:0003007 IMP heart morphogenesis
GO:0005102 IDA receptor binding
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0007498 IMP mesoderm development
GO:0007595 IMP lactation
GO:0008083 IDA growth factor activity
GO:0008201 IDA heparin binding
GO:0008283 IMP cell proliferation
GO:0008284 IDA positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0016477 IDA cell migration
GO:0022408 IGI negative regulation of cell-cell adhesion
GO:0030324 IMP lung development
GO:0030823 ISO regulation of cGMP metabolic process
GO:0030855 IMP epithelial cell differentiation
GO:0031077 IMP post-embryonic camera-type eye development
GO:0040007 IMP growth
GO:0042462 IMP eye photoreceptor cell development
GO:0043066 IMP negative regulation of apoptotic process
GO:0043117 IDA positive regulation of vascular permeability
GO:0043129 IMP surfactant homeostasis
GO:0043183 IDA vascular endothelial growth factor receptor 1 binding
GO:0043184 IPI vascular endothelial growth factor receptor 2 binding
GO:0045766 IDA positive regulation of angiogenesis
GO:0046982 ISO protein heterodimerization activity
GO:0048010 IDA vascular endothelial growth factor receptor signaling pathway
GO:0048469 IMP cell maturation
GO:0048514 IDA blood vessel morphogenesis
GO:0048593 IMP camera-type eye morphogenesis
GO:0048739 IMP cardiac muscle fiber development
GO:0048754 IDA branching morphogenesis of an epithelial tube
GO:0048844 IMP artery morphogenesis
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0050840 IDA extracellular matrix binding
GO:0051781 IEA positive regulation of cell division
GO:0060319 IMP primitive erythrocyte differentiation
GO:0060426 IDA lung vasculature development
GO:0060749 IMP mammary gland alveolus development
GO:0071456 ISO cellular response to hypoxia
GO:0071542 IGI dopaminergic neuron differentiation
GO:1901492 IDA positive regulation of lymphangiogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000230480 VEGFA-009 protein_coding Homo_sapiens 0 1033
ENST00000324450 VEGFA-011 protein_coding Homo_sapiens 0 1072
ENST00000372055 VEGFA-004 protein_coding Homo_sapiens 0 1098
ENST00000372064 VEGFA-002 protein_coding Homo_sapiens 0 1535
ENST00000372067 VEGFA-001 protein_coding Homo_sapiens 0 3175
ENST00000372077 VEGFA-019 protein_coding Homo_sapiens 0 1535
ENST00000413642 VEGFA-012 protein_coding Homo_sapiens 0 1098
ENST00000417285 VEGFA-014 protein_coding Homo_sapiens 0 1254
ENST00000425836 VEGFA-003 protein_coding Homo_sapiens 0 1098
ENST00000457104 VEGFA-022 protein_coding Homo_sapiens 0 462
ENST00000476772 VEGFA-005 retained_intron Homo_sapiens 0 1391
ENST00000480614 VEGFA-007 retained_intron Homo_sapiens 0 1535
ENST00000482630 VEGFA-013 protein_coding Homo_sapiens 0 1323
ENST00000493786 VEGFA-010 retained_intron Homo_sapiens 0 414
ENST00000497139 VEGFA-008 retained_intron Homo_sapiens 0 1465
ENST00000512683 VEGFA-006 retained_intron Homo_sapiens 0 340
ENST00000518538 VEGFA-017 retained_intron Homo_sapiens 0 606
ENST00000518689 VEGFA-023 protein_coding Homo_sapiens 0 488
ENST00000518824 VEGFA-024 protein_coding Homo_sapiens 0 713
ENST00000519767 VEGFA-015 protein_coding Homo_sapiens 0 985
ENST00000520265 VEGFA-016 protein_coding Homo_sapiens 0 237
ENST00000520948 VEGFA-020 protein_coding Homo_sapiens 0 686
ENST00000523125 VEGFA-025 protein_coding Homo_sapiens 0 645
ENST00000523873 VEGFA-021 protein_coding Homo_sapiens 0 553
ENST00000523950 VEGFA-018 protein_coding Homo_sapiens 0 1133
ENST00000611736 VEGFA-201 protein_coding Homo_sapiens 0 1753
ENST00000615393 VEGFA-202 protein_coding Homo_sapiens 0 1530
ENST00000617771 VEGFA-203 protein_coding Homo_sapiens 0 1539
ENST00000621747 VEGFA-204 protein_coding Homo_sapiens 0 3169

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