C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myosin, heavy polypeptide 6, cardiac muscle, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000081857 Myh6-201 ENSMUSG00000040752 10090 - 14:54941921-54966607 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000081857
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000081857 0.064±0.02 0.062±0.04 0.039±0.00 0.112±0.00 0.098±0.04 0.046±0.02 1615.017±58.74 0.134±0.07 0.011±0.01 28.156±7.04 0.292±0.07 0.090±0.04 0.038±0.02 0.037±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090C CIL_00090C_0002 VISTA 14:54638004-55241428
CIL_0009BW CIL_0009BW_0002 VISTA 14:54696106-55297707
CIL_0008Q4 CIL_0008Q4_0002 VISTA 14:54696894-55297224
CIL_0008QH CIL_0008QH_0002 VISTA 14:54703667-55304830
CIL_00051L CIL_00051L_0002 CGP 14:54936470-54966927
CIL_0004Z7 CIL_0004Z7_0008 CGP 14:54941921-54994634

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000146 IMP microfilament motor activity
GO:0001701 IMP in utero embryonic development
GO:0001725 IDA stress fiber
GO:0002026 IMP regulation of the force of heart contraction
GO:0002027 IMP regulation of heart rate
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005925 IEA focal adhesion
GO:0006200 IEA ATP catabolic process
GO:0006936 IEA muscle contraction
GO:0006941 IMP striated muscle contraction
GO:0007512 IMP adult heart development
GO:0007522 IMP visceral muscle development
GO:0008016 IMP regulation of heart contraction
GO:0008217 IMP regulation of blood pressure
GO:0016459 IDA myosin complex
GO:0016887 IEA ATPase activity
GO:0019901 IEA protein kinase binding
GO:0030016 IDA myofibril
GO:0030018 IDA Z disc
GO:0030048 IMP actin filament-based movement
GO:0030049 IEA muscle filament sliding
GO:0030239 IMP myofibril assembly
GO:0030509 IDA BMP signaling pathway
GO:0030898 IEA actin-dependent ATPase activity
GO:0032982 IEA myosin filament
GO:0043462 IMP regulation of ATPase activity
GO:0045214 IMP sarcomere organization
GO:0048739 IMP cardiac muscle fiber development
GO:0051015 IEA actin filament binding
GO:0055009 IEA atrial cardiac muscle tissue morphogenesis
GO:0055010 IEA ventricular cardiac muscle tissue morphogenesis
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060420 IDA regulation of heart growth

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000150162 si:ch211-24n20.3-001 protein_coding Danio_rerio 0 3969
ENSDART00000066527 smyhc3-201 protein_coding Danio_rerio 0 3943
ENSDART00000150060 smyhc3-001 protein_coding Danio_rerio 0 3943
ENSDART00000135233 si:ch211-24n20.3-201 protein_coding Danio_rerio 0 3921
ENSDART00000137082 CU633479.6-201 protein_coding Danio_rerio 0 3916
ENSDART00000133338 CR450736.2-201 protein_coding Danio_rerio 0 3888
ENSDART00000137989 CU633479.5-201 protein_coding Danio_rerio 0 3879
ENSDART00000056849 smyhc2-001 protein_coding Danio_rerio 0 3864
ENSDART00000056853 smyhc1-203 protein_coding Danio_rerio 0 3698
ENSDART00000051360 MYH13 (3 of 10)-201 protein_coding Danio_rerio 0 2745
ENSDART00000122889 myhz1.3-001 protein_coding Danio_rerio 0 2628
ENSDART00000051361 myhz2-201 protein_coding Danio_rerio 0 2623
ENSDART00000126873 myhz2-001 protein_coding Danio_rerio 0 2623
ENSDART00000051362 myhc4-201 protein_coding Danio_rerio 0 2623
ENSDART00000125917 myhc4-001 protein_coding Danio_rerio 0 2623
ENSDART00000098060 myhz1.1-201 protein_coding Danio_rerio 0 2604
ENSDART00000123003 myhz1.1-001 protein_coding Danio_rerio 0 2604
ENSDART00000098072 myhz1.1-202 protein_coding Danio_rerio 0 2590
ENSDART00000098067 myhz1.2-201 protein_coding Danio_rerio 0 2588
ENSDART00000131983 myhz1.2-001 protein_coding Danio_rerio 0 2588
ENSDART00000109263 myhz1.1-203 protein_coding Danio_rerio 0 2555
ENSDART00000139917 myha-001 protein_coding Danio_rerio 0 2495
ENSDART00000156295 myhb-001 protein_coding Danio_rerio 0 2303
ENSDART00000026257 myhb-201 protein_coding Danio_rerio 0 2281
ENSDART00000123920 MYH13 (5 of 10)-202 protein_coding Danio_rerio 0 2124
ENSDART00000097316 myh7ba-201 protein_coding Danio_rerio 0 1881
ENSDART00000152186 myh7ba-001 protein_coding Danio_rerio 0 1877
ENSDART00000045928 smyhc1-202 protein_coding Danio_rerio 0 1740
ENSDART00000004536 smyhc1-201 protein_coding Danio_rerio 0 1725
ENSDART00000135295 MYH13 (9 of 10)-201 protein_coding Danio_rerio 0 1164
ENSDART00000075210 protein_coding Danio_rerio 0 1110
ENSDART00000130036 MYH13 (5 of 10)-201 protein_coding Danio_rerio 0 761
ENSDART00000127125 myhz1.3-201 protein_coding Danio_rerio 0 571
ENSDART00000124862 smyhc2-003 protein_coding Danio_rerio 0 484
ENSDART00000098111 myha-201 protein_coding Danio_rerio 0 370
ENSDART00000149247 smyhc2-004 retained_intron Danio_rerio 0 259
ENSDART00000147211 smyhc2-002 retained_intron Danio_rerio 1.99965e-42 180
ENST00000226207 MYH1-001 protein_coding Homo_sapiens 0 3265
ENST00000245503 MYH2-001 protein_coding Homo_sapiens 0 3182
ENST00000252172 MYH13-001 protein_coding Homo_sapiens 0 2126
ENST00000255381 MYH4-001 protein_coding Homo_sapiens 0 3022
ENST00000262873 MYH7B-001 protein_coding Homo_sapiens 0 1881
ENST00000355349 MYH7-001 protein_coding Homo_sapiens 0 6938
ENST00000356287 MYH6-001 protein_coding Homo_sapiens 0 8072
ENST00000376970 MYH14-202 protein_coding Homo_sapiens 0 193
ENST00000397183 MYH2-201 protein_coding Homo_sapiens 0 3182
ENST00000405093 MYH6-201 protein_coding Homo_sapiens 0 8078
ENST00000413734 MYH16-003 processed_transcript Homo_sapiens 0 392
ENST00000418404 MYH13-003 protein_coding Homo_sapiens 0 2126
ENST00000420805 MYH2-002 protein_coding Homo_sapiens 0 316
ENST00000425460 MYH14-203 protein_coding Homo_sapiens 0 193
ENST00000439784 MYH16-001 unitary_pseudogene Homo_sapiens 0 704
ENST00000440075 MYH14-204 protein_coding Homo_sapiens 2e-35 156
ENST00000470929 MYH7B-002 retained_intron Homo_sapiens 3e-25 121
ENST00000532183 MYH2-006 protein_coding Homo_sapiens 0 1177
ENST00000557461 MYH6-002 retained_intron Homo_sapiens 0 2265
ENST00000578017 MYH2-009 protein_coding Homo_sapiens 0 392
ENST00000579489 MYH3-004 retained_intron Homo_sapiens 0 289
ENST00000583535 MYH3-001 protein_coding Homo_sapiens 0 3184
ENST00000596571 MYH14-008 protein_coding Homo_sapiens 0 193
ENST00000598205 MYH14-006 protein_coding Homo_sapiens 0 193
ENST00000599920 MYH14-007 protein_coding Homo_sapiens 0 193
ENST00000601313 MYH14-001 protein_coding Homo_sapiens 0 193
ENST00000618182 MYH7B-201 protein_coding Homo_sapiens 0 1881
ENST00000621918 MYH13-201 protein_coding Homo_sapiens 0 2126
ENST00000622564 MYH2-202 protein_coding Homo_sapiens 0 1177

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