C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myosin, heavy chain 6, cardiac muscle, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000405093 MYH6-201 ENSG00000197616 9606 - 14:23381990-23408277 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverMuscleOvaryPlacentaTestisENST00000405093
Transcript ID Liver Muscle Ovary Placenta Testis
ENST00000405093 0.045±0.00 21.706±0.00 0.037±0.00 0.311±0.00 0.255±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090C CIL_00090C_0001 VISTA 14:23078458-23681621
CIL_0009BW CIL_0009BW_0001 VISTA 14:23137378-23739005
CIL_0008Q4 CIL_0008Q4_0001 VISTA 14:23138150-23738498
CIL_0008QH CIL_0008QH_0001 VISTA 14:23142404-23743714
CIL_00051L CIL_00051L_0001 CGP 14:23376808-23408277
CIL_0004Z7 CIL_0004Z7_0007 CGP 14:23381990-23435718

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000146 ISS microfilament motor activity
GO:0001701 ISS in utero embryonic development
GO:0001725 IEA stress fiber
GO:0002026 ISS regulation of the force of heart contraction
GO:0002027 IDA regulation of heart rate
GO:0003774 IEA motor activity
GO:0003779 IEA actin binding
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005859 TAS muscle myosin complex
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006936 IDA muscle contraction
GO:0006941 ISS striated muscle contraction
GO:0007512 IMP adult heart development
GO:0007522 ISS visceral muscle development
GO:0008016 ISS regulation of heart contraction
GO:0008217 ISS regulation of blood pressure
GO:0016459 TAS:IEA myosin complex
GO:0016887 IDA ATPase activity
GO:0019901 IPI protein kinase binding
GO:0030016 ISS myofibril
GO:0030017 TAS sarcomere
GO:0030018 IEA Z disc
GO:0030048 IEA actin filament-based movement
GO:0030049 IMP muscle filament sliding
GO:0030239 ISS myofibril assembly
GO:0030509 IEA BMP signaling pathway
GO:0030898 IMP actin-dependent ATPase activity
GO:0032982 IEA myosin filament
GO:0043462 ISS regulation of ATPase activity
GO:0045214 ISS sarcomere organization
GO:0048739 ISS cardiac muscle fiber development
GO:0055009 IMP atrial cardiac muscle tissue morphogenesis
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060420 IEA regulation of heart growth

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000081857 Myh6-201 protein_coding Mus_musculus 0 8078
ENSMUST00000168485 Myh7-201 protein_coding Mus_musculus 0 7114
ENSMUST00000102803 Myh7-001 protein_coding Mus_musculus 0 7114
ENSMUST00000145322 Myh6-001 protein_coding Mus_musculus 0 4687
ENSDART00000150162 si:ch211-24n20.3-001 protein_coding Danio_rerio 0 3927
ENSDART00000056849 smyhc2-001 protein_coding Danio_rerio 0 3897
ENSDART00000135233 si:ch211-24n20.3-201 protein_coding Danio_rerio 0 3882
ENSDART00000137082 CU633479.6-201 protein_coding Danio_rerio 0 3877
ENSDART00000066527 smyhc3-201 protein_coding Danio_rerio 0 3856
ENSDART00000150060 smyhc3-001 protein_coding Danio_rerio 0 3856
ENSDART00000137989 CU633479.5-201 protein_coding Danio_rerio 0 3851
ENSDART00000133338 CR450736.2-201 protein_coding Danio_rerio 0 3821
ENSMUST00000170159 Myh2-201 protein_coding Mus_musculus 0 3786
ENSMUST00000018641 Myh2-001 protein_coding Mus_musculus 0 3786
ENSDART00000056853 smyhc1-203 protein_coding Danio_rerio 0 3740
ENSMUST00000075734 Myh1-201 protein_coding Mus_musculus 0 3712
ENSMUST00000018637 Myh1-003 protein_coding Mus_musculus 0 3712
ENSMUST00000124516 Myh1-001 protein_coding Mus_musculus 0 3712
ENSMUST00000170942 Myh4-201 protein_coding Mus_musculus 0 3640
ENSMUST00000018632 Myh4-001 protein_coding Mus_musculus 0 3640
ENSMUST00000019625 Myh8-001 protein_coding Mus_musculus 0 3607
ENSMUST00000165221 Myh3-202 protein_coding Mus_musculus 0 3415
ENSMUST00000007301 Myh3-201 protein_coding Mus_musculus 0 3415
ENSMUST00000108689 Myh3-001 protein_coding Mus_musculus 0 3415
ENSMUST00000081911 Myh13-201 protein_coding Mus_musculus 0 3127
ENSMUST00000180845 Myh13-002 protein_coding Mus_musculus 0 3127
ENSMUST00000108684 Myh13-001 protein_coding Mus_musculus 0 3127
ENSDART00000128784 vmhcl-001 protein_coding Danio_rerio 0 3109
ENSDART00000078958 vmhcl-201 protein_coding Danio_rerio 0 3027
ENSDART00000099532 vmhc-001 protein_coding Danio_rerio 0 2929
ENSDART00000125917 myhc4-001 protein_coding Danio_rerio 0 2551
ENSDART00000051362 myhc4-201 protein_coding Danio_rerio 0 2540
ENSDART00000122889 myhz1.3-001 protein_coding Danio_rerio 0 2540
ENSDART00000098060 myhz1.1-201 protein_coding Danio_rerio 0 2521
ENSDART00000123003 myhz1.1-001 protein_coding Danio_rerio 0 2521
ENSDART00000098067 myhz1.2-201 protein_coding Danio_rerio 0 2510
ENSDART00000131983 myhz1.2-001 protein_coding Danio_rerio 0 2510
ENSDART00000098072 myhz1.1-202 protein_coding Danio_rerio 0 2507
ENSDART00000051361 myhz2-201 protein_coding Danio_rerio 0 2495
ENSDART00000126873 myhz2-001 protein_coding Danio_rerio 0 2495
ENSDART00000109263 myhz1.1-203 protein_coding Danio_rerio 0 2488
ENSDART00000139917 myha-001 protein_coding Danio_rerio 0 2484
ENSDART00000156295 myhb-001 protein_coding Danio_rerio 0 2121
ENSDART00000026257 myhb-201 protein_coding Danio_rerio 0 2098
ENSDART00000123920 MYH13 (5 of 10)-202 protein_coding Danio_rerio 0 2050
ENSDART00000051360 MYH13 (3 of 10)-201 protein_coding Danio_rerio 0 1749
ENSDART00000045928 smyhc1-202 protein_coding Danio_rerio 0 1694
ENSDART00000004536 smyhc1-201 protein_coding Danio_rerio 0 1674
ENSMUST00000108686 Myh8-002 retained_intron Mus_musculus 0 1585
ENSMUST00000149852 Myh7-002 retained_intron Mus_musculus 0 1572
ENSMUST00000092995 Myh7b-001 protein_coding Mus_musculus 0 1465
ENSDART00000152186 myh7ba-001 protein_coding Danio_rerio 0 1273
ENSDART00000097316 myh7ba-201 protein_coding Danio_rerio 0 1271
ENSDART00000075210 protein_coding Danio_rerio 0 1101
ENSDART00000135295 MYH13 (9 of 10)-201 protein_coding Danio_rerio 0 1066
ENSDART00000137438 myh7bb-001 protein_coding Danio_rerio 0 682
ENSDART00000147260 MYH7B (3 of 3)-201 protein_coding Danio_rerio 0 682
ENSMUST00000139052 Myh8-004 retained_intron Mus_musculus 0 621
ENSDART00000127125 myhz1.3-201 protein_coding Danio_rerio 0 555
ENSDART00000124862 smyhc2-003 protein_coding Danio_rerio 0 529
ENSDART00000123565 vmhcl-004 protein_coding Danio_rerio 0 420
ENSDART00000098111 myha-201 protein_coding Danio_rerio 0 387
ENSMUST00000181027 Myh13-004 protein_coding Mus_musculus 0 377
ENSMUST00000134256 Myh6-003 protein_coding Mus_musculus 0 357
ENSMUST00000124930 Myh6-004 protein_coding Mus_musculus 0 351
ENSMUST00000108685 Myh8-003 protein_coding Mus_musculus 0 294
ENSDART00000141922 vmhcl-002 protein_coding Danio_rerio 0 279
ENSMUST00000111456 Myh6-002 protein_coding Mus_musculus 0 231
ENSMUST00000131892 Myh6-005 retained_intron Mus_musculus 0 209
ENSDART00000147211 smyhc2-002 retained_intron Danio_rerio 4.06377e-44 185
ENSMUST00000107900 Myh14-201 protein_coding Mus_musculus 1.99993e-41 176
ENSMUST00000182648 Myh14-007 protein_coding Mus_musculus 1.99993e-41 176
ENSMUST00000048102 Myh14-001 protein_coding Mus_musculus 1.99993e-41 176
ENSMUST00000107899 Myh14-002 protein_coding Mus_musculus 1.99993e-41 176
ENSDART00000105232 myh9a-202 protein_coding Danio_rerio 0.000000004 69
ENSDART00000011353 myh9a-201 protein_coding Danio_rerio 0.000000004 69
ENSDART00000149823 myh9a-001 protein_coding Danio_rerio 0.000000004 69
ENSDART00000143547 myo15ab-001 protein_coding Danio_rerio 0.0000006 62

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