C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: B cell CLL/lymphoma 11A (zinc finger protein)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109514 Bcl11a-006 ENSMUSG00000000861 10090 + 11:24078173-24168429 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000109514
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000109514 0.010±0.00 0.325±0.09 0.076±0.01 8.852±4.60 1.290±0.15 0.371±0.12 0.052±0.01 0.057±0.02 1.695±1.72 0.112±0.02 0.081±0.13 1.017±0.46 0.060±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PG CIL_0008PG_0002 VISTA 11:23715166-24317101
CIL_0009DA CIL_0009DA_0002 VISTA 11:23762086-24363576
CIL_0008GM CIL_0008GM_0002 VISTA 11:23795054-24396665
CIL_0008WW CIL_0008WW_0002 VISTA 11:24012332-24614280
CIL_000881 CIL_000881_0002 VISTA 11:24029867-24633908
CIL_0007LM CIL_0007LM_0002 UCNEbase 11:24062983-26981636
CIL_0008BH CIL_0008BH_0002 VISTA 11:24070835-24671855

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676 IEA nucleic acid binding
GO:0003714 IDA transcription corepressor activity
GO:0005634 IDA nucleus
GO:0010629 IMP negative regulation of gene expression
GO:0010976 IEA positive regulation of neuron projection development
GO:0010977 IEA negative regulation of neuron projection development
GO:0030183 IMP B cell differentiation
GO:0030217 IMP T cell differentiation
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048671 IEA negative regulation of collateral sprouting
GO:0048672 IEA positive regulation of collateral sprouting
GO:0050773 IEA regulation of dendrite development
GO:2000171 IEA negative regulation of dendrite development
GO:2001141 IDA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000087426 bcl11aa-001 protein_coding Danio_rerio 0 540
ENSDART00000140827 bcl11ab-001 protein_coding Danio_rerio 2e-17 97
ENSDART00000092040 bcl11ab-201 protein_coding Danio_rerio 2e-16 94
ENST00000335712 BCL11A-001 protein_coding Homo_sapiens 0 8074
ENST00000356842 BCL11A-002 protein_coding Homo_sapiens 0 3997
ENST00000358510 BCL11A-006 protein_coding Homo_sapiens 0 3493
ENST00000359629 BCL11A-003 protein_coding Homo_sapiens 0 1404
ENST00000409351 BCL11A-004 processed_transcript Homo_sapiens 0 979
ENST00000477659 BCL11A-008 processed_transcript Homo_sapiens 0 4076
ENST00000479026 BCL11A-013 processed_transcript Homo_sapiens 1e-20 104
ENST00000489183 BCL11A-011 processed_transcript Homo_sapiens 0 355
ENST00000489516 BCL11A-007 processed_transcript Homo_sapiens 0 963
ENST00000492272 BCL11A-010 processed_transcript Homo_sapiens 0 427

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