C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: prospero homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000177288 Prox1-002 ENSMUSG00000010175 10090 - 1:190121775-190170233 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposePlacentaENSMUST00000177288
Transcript ID Adipose Placenta
ENSMUST00000177288 0.037±0.00 0.071±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089Q CIL_00089Q_0002 VISTA 1:189761322-190362331
CIL_0003Z6 CIL_0003Z6_0002 CGP 1:189880492-190170714
CIL_0007J3 CIL_0007J3_0002 UCNEbase 1:189990273-190853986

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001709 IMP cell fate determination
GO:0001945 IMP lymph vessel development
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0002194 IMP hepatocyte cell migration
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007623 IEP circadian rhythm
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0010468 IMP regulation of gene expression
GO:0021542 IMP dentate gyrus development
GO:0021707 IMP cerebellar granule cell differentiation
GO:0030240 IMP skeletal muscle thin filament assembly
GO:0042752 ISS regulation of circadian rhythm
GO:0043565 IDA sequence-specific DNA binding
GO:0045446 IMP endothelial cell differentiation
GO:0045787 IMP positive regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046619 IEP optic placode formation involved in camera-type eye formation
GO:0048839 IMP inner ear development
GO:0048845 IMP venous blood vessel morphogenesis
GO:0055005 IMP ventricular cardiac myofibril assembly
GO:0055009 IMP atrial cardiac muscle tissue morphogenesis
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060059 IEP embryonic retina morphogenesis in camera-type eye
GO:0060214 IMP endocardium formation
GO:0060298 IMP positive regulation of sarcomere organization
GO:0060412 IMP ventricular septum morphogenesis
GO:0060414 IMP aorta smooth muscle tissue morphogenesis
GO:0060421 IMP positive regulation of heart growth
GO:0060836 IMP lymphatic endothelial cell differentiation
GO:0061114 IMP branching involved in pancreas morphogenesis
GO:0070309 IMP lens fiber cell morphogenesis
GO:0070365 IEP hepatocyte differentiation
GO:0072574 IMP hepatocyte proliferation
GO:0090425 IMP acinar cell differentiation
GO:0097150 IMP neuronal stem cell maintenance
GO:1901978 IMP positive regulation of cell cycle checkpoint
GO:2000179 IMP positive regulation of neural precursor cell proliferation
GO:2000979 IMP positive regulation of forebrain neuron differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000077476 prox1a-001 protein_coding Danio_rerio 0 1232
ENST00000261454 PROX1-201 protein_coding Homo_sapiens 0 3559
ENST00000366958 PROX1-001 protein_coding Homo_sapiens 0 3358
ENST00000435016 PROX1-002 protein_coding Homo_sapiens 0 3552
ENST00000471129 PROX1-004 protein_coding Homo_sapiens 0 1271
ENST00000498508 PROX1-202 protein_coding Homo_sapiens 0 3358
ENST00000607425 PROX1-006 protein_coding Homo_sapiens 0 826

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