C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 6 (neurotransmitter transporter), member 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000253122 SLC6A8-002 ENSG00000130821 9606 + X:153688099-153696593 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253122
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253122 13.053±0.00 3.996±0.00 2.299±0.00 29.824±26.80 8.785±7.13 14.424±13.04 20.040±18.41 40.398±0.00 0.422±0.03 4.830±0.00 14.227±5.68 6.794±3.79 18.177±2.35 13.519±2.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001UZ CIL_0001UZ_0001 CGP X:153642492-153689010
CIL_0001UY CIL_0001UY_0001 CGP X:153669730-153696593
CIL_0001UX CIL_0001UX_0001 CGP X:153688099-153724697

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005308 NAS creatine transmembrane transporter activity
GO:0005309 IEA creatine:sodium symporter activity
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005575 ND cellular_component
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006600 TAS creatine metabolic process
GO:0006810 TAS transport
GO:0006814 IEA sodium ion transport
GO:0006836 IEA neurotransmitter transport
GO:0006936 TAS muscle contraction
GO:0008150 ND biological_process
GO:0015881 NAS creatine transport
GO:0016021 TAS:IEA integral component of membrane
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:1902598 IEA creatine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033752 Slc6a8-001 protein_coding Mus_musculus 0 3319
ENSMUST00000114465 Slc6a8-002 protein_coding Mus_musculus 0 2959
ENSMUST00000114467 Slc6a8-201 protein_coding Mus_musculus 0 2952
ENSMUST00000164449 Slc6a8-006 protein_coding Mus_musculus 0 2730
ENSMUST00000168831 Slc6a8-003 protein_coding Mus_musculus 0 2630
ENSMUST00000114464 Slc6a8-004 nonsense_mediated_decay Mus_musculus 0 2074
ENSMUST00000170614 Slc6a8-009 retained_intron Mus_musculus 0 1585
ENSMUST00000168764 Slc6a8-013 retained_intron Mus_musculus 0 813
ENSMUST00000146796 Slc6a8-011 retained_intron Mus_musculus 0 791
ENSMUST00000171398 Slc6a8-012 protein_coding Mus_musculus 0 627
ENSMUST00000166200 Slc6a8-010 processed_transcript Mus_musculus 0 547
ENSMUST00000167828 Slc6a8-014 retained_intron Mus_musculus 0 460
ENSMUST00000170574 Slc6a8-015 retained_intron Mus_musculus 0 333
ENSDART00000092131 si:ch211-117c9.5-001 protein_coding Danio_rerio 9.99967e-42 176
ENSDART00000041794 slc6a6a-201 protein_coding Danio_rerio 1e-36 159
ENSDART00000146306 slc6a6a-001 protein_coding Danio_rerio 1e-36 159
ENSDART00000149136 si:ch211-117c9.5-002 protein_coding Danio_rerio 3e-23 115
ENSDART00000129303 SLC6A3-201 protein_coding Danio_rerio 0.00000000005 75
ENSMUST00000124406 Slc6a19-005 nonsense_mediated_decay Mus_musculus 0.00002 57
ENSMUST00000132085 Slc6a19-003 retained_intron Mus_musculus 0.00002 57
ENSMUST00000022048 Slc6a19-001 protein_coding Mus_musculus 0.00002 57

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