C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transient receptor potential cation channel, subfamily V, member 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000261740 TRPV4-001 ENSG00000111199 9606 - 12:109783087-109833401 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLiverOvaryPlacentaENST00000261740
Transcript ID Adipose Brain Colon Heart Kidney Liver Ovary Placenta
ENST00000261740 0.178±0.00 0.082±0.00 0.042±0.00 0.093±0.00 3.392±0.00 0.382±0.00 0.579±0.14 3.630±1.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001JO CIL_0001JO_0002 CGP 12:109714228-109833401
CIL_00062E CIL_00062E_0002 CGP 12:109783085-109880488

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 ISS actin binding
GO:0005080 ISS protein kinase C binding
GO:0005216 IEA ion channel activity
GO:0005261 IDA cation channel activity
GO:0005262 IDA calcium channel activity
GO:0005515 IEA protein binding
GO:0005516 IMP calmodulin binding
GO:0005524 IEA ATP binding
GO:0005881 ISS cytoplasmic microtubule
GO:0005886 ISS plasma membrane
GO:0005912 ISS adherens junction
GO:0005925 ISS focal adhesion
GO:0006811 IEA ion transport
GO:0006816 NAS calcium ion transport
GO:0006874 IDA cellular calcium ion homeostasis
GO:0006884 TAS cell volume homeostasis
GO:0007015 ISS actin filament organization
GO:0007043 ISS cell-cell junction assembly
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007231 ISS osmosensory signaling pathway
GO:0008017 ISS microtubule binding
GO:0008219 IEA cell death
GO:0009612 TAS response to mechanical stimulus
GO:0010977 ISS negative regulation of neuron projection development
GO:0016020 IEA membrane
GO:0016021 IEA:NAS integral component of membrane
GO:0019901 IPI protein kinase binding
GO:0030027 ISS lamellipodium
GO:0030175 ISS filopodium
GO:0030426 ISS growth cone
GO:0030864 ISS cortical actin cytoskeleton
GO:0031117 ISS positive regulation of microtubule depolymerization
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032587 ISS ruffle membrane
GO:0034220 TAS ion transmembrane transport
GO:0034605 ISS cellular response to heat
GO:0042169 ISS SH2 domain binding
GO:0043014 ISS alpha-tubulin binding
GO:0043622 ISS cortical microtubule organization
GO:0046785 ISS microtubule polymerization
GO:0048487 ISS beta-tubulin binding
GO:0051015 ISS actin filament binding
GO:0055085 TAS:IEA transmembrane transport
GO:0070509 ISS calcium ion import
GO:0070588 TAS calcium ion transmembrane transport
GO:0071470 ISS cellular response to osmotic stress
GO:0071476 ISS cellular hypotonic response

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000071968 Trpv4-001 protein_coding Mus_musculus 0 3158
ENSMUST00000112225 Trpv4-002 protein_coding Mus_musculus 0 3155
ENSMUST00000133019 Trpv4-004 retained_intron Mus_musculus 0 2372
ENSMUST00000112222 Trpv4-005 protein_coding Mus_musculus 0 2194
ENSMUST00000112217 Trpv4-007 protein_coding Mus_musculus 0 1594
ENSMUST00000112219 Trpv4-006 protein_coding Mus_musculus 0 1594
ENSMUST00000141828 Trpv4-003 processed_transcript Mus_musculus 0 695
ENSMUST00000138853 Trpv1-004 protein_coding Mus_musculus 0 198
ENSMUST00000108470 Trpv1-003 protein_coding Mus_musculus 0 198
ENSMUST00000006106 Trpv1-002 protein_coding Mus_musculus 0 198
ENSMUST00000102526 Trpv1-001 protein_coding Mus_musculus 0 198

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