C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histone deacetylase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000305264 HDAC3-001 ENSG00000171720 9606 - 5:141620876-141636870 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305264
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305264 8.265±0.00 9.141±0.00 8.699±4.23 5.001±2.04 2.935±1.39 7.122±5.46 9.078±0.98 7.507±4.53 5.789±4.13 7.042±6.50 12.916±9.10 16.216±8.59 9.074±1.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006QD CIL_0006QD_0001 CGP 5:141515016-141636870
CIL_0006QE CIL_0006QE_0001 CGP 5:141620876-141641077

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003714 IMP transcription corepressor activity
GO:0004407 TAS:IEA histone deacetylase activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 TAS cytoplasm
GO:0005876 IDA spindle microtubule
GO:0006351 IEA transcription, DNA-templated
GO:0006476 IDA protein deacetylation
GO:0007219 TAS Notch signaling pathway
GO:0007346 IEA regulation of mitotic cell cycle
GO:0008134 TAS transcription factor binding
GO:0016568 TAS chromatin modification
GO:0016575 IEA histone deacetylation
GO:0017053 IDA transcriptional repressor complex
GO:0019899 IPI enzyme binding
GO:0030332 IPI cyclin binding
GO:0031490 IEA chromatin DNA binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032922 IEA circadian regulation of gene expression
GO:0033558 IDA protein deacetylase activity
GO:0040014 IEA regulation of multicellular organism growth
GO:0042826 IPI histone deacetylase binding
GO:0043066 TAS negative regulation of apoptotic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045786 TAS negative regulation of cell cycle
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0046329 IMP negative regulation of JNK cascade
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051225 IMP spindle assembly
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043498 Hdac3-001 protein_coding Mus_musculus 0 1934
ENSDART00000054626 hdac3-001 protein_coding Danio_rerio 0 830
ENSMUST00000153945 Hdac3-002 processed_transcript Mus_musculus 0 778
ENSMUST00000144471 Hdac3-004 retained_intron Mus_musculus 0 507
ENSMUST00000143660 Hdac3-003 retained_intron Mus_musculus 0 466
ENSDART00000145250 hdac3-002 processed_transcript Danio_rerio 0 302

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