C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NK2 homeobox 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000325017 NKX2-6-001 ENSG00000180053 9606 - 8:23702451-23706598 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartENST00000325017
Transcript ID Heart
ENST00000325017 0.159±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008FQ CIL_0008FQ_0001 VISTA 8:23193785-23795287
CIL_0007YD CIL_0007YD_0001 VISTA 8:23207989-23809472

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IC nucleus
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007507 IEA heart development
GO:0008284 ISS positive regulation of cell proliferation
GO:0021854 ISS hypothalamus development
GO:0030154 ISS cell differentiation
GO:0035050 ISS embryonic heart tube development
GO:0043066 ISS negative regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0043586 ISS tongue development
GO:0048565 ISS digestive tract development
GO:0055014 ISS atrial cardiac muscle cell development
GO:0055015 ISS ventricular cardiac muscle cell development
GO:0060037 ISS pharyngeal system development
GO:0060039 ISS pericardium development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062437 Nkx2-6-001 protein_coding Mus_musculus 0 361
ENSMUST00000015723 Nkx2-5-001 protein_coding Mus_musculus 0 272
ENSMUST00000067020 Nkx2-4-001 protein_coding Mus_musculus 0 195
ENSMUST00000001536 Nkx2-1-002 protein_coding Mus_musculus 9e-33 145
ENSMUST00000178477 Nkx2-1-001 protein_coding Mus_musculus 9e-33 145
ENSMUST00000072631 Nkx2-9-001 protein_coding Mus_musculus 3e-23 113
ENSDART00000007829 nkx2.1a-001 protein_coding Danio_rerio 3e-17 94
ENSDART00000153363 protein_coding Danio_rerio 0.000001 58
ENSDART00000123722 msxd-202 protein_coding Danio_rerio 0.00002 55
ENSDART00000003441 msxd-201 protein_coding Danio_rerio 0.00002 55

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