C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: trio Rho guanine nucleotide exchange factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000344204 TRIO-001 ENSG00000038382 9606 + 5:14143702-14510204 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000344204
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000344204 2.251±0.00 2.662±0.00 1.424±0.00 2.618±0.63 1.613±0.00 3.574±0.00 1.108±0.00 1.282±0.02 2.769±1.08 0.376±0.00 2.743±1.06 2.519±1.84

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0007185 TAS transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007411 TAS axon guidance
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019899 IEA enzyme binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 TAS positive regulation of GTPase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000090247 Trio-201 protein_coding Mus_musculus 0 12200
ENSDART00000087055 trioa-201 protein_coding Danio_rerio 0 4161
ENSDART00000144275 trioa-001 protein_coding Danio_rerio 0 4161
ENSMUST00000114961 Kalrn-012 protein_coding Mus_musculus 0 1437
ENSMUST00000076810 Kalrn-011 protein_coding Mus_musculus 0 1437
ENSMUST00000142817 Kalrn-009 protein_coding Mus_musculus 0 1437
ENSMUST00000114949 Kalrn-003 protein_coding Mus_musculus 0 1315
ENSMUST00000114960 Kalrn-001 protein_coding Mus_musculus 0 1315
ENSMUST00000114947 Kalrn-018 protein_coding Mus_musculus 0 1264
ENSMUST00000114954 Kalrn-007 protein_coding Mus_musculus 0 1206
ENSMUST00000114953 Kalrn-005 protein_coding Mus_musculus 0 1206
ENSMUST00000089655 Kalrn-004 protein_coding Mus_musculus 0 1206
ENSMUST00000151491 Kalrn-002 protein_coding Mus_musculus 0 1144
ENSMUST00000137216 Kalrn-006 retained_intron Mus_musculus 0 252

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