C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: valosin containing protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000358901 VCP-001 ENSG00000165280 9606 - 9:35056064-35073249 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358901
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358901 10.417±0.00 8.562±0.00 6.114±2.57 6.576±2.55 4.700±0.00 10.065±4.98 6.339±0.10 5.029±0.00 9.592±0.00 13.159±0.60 20.217±10.37 18.308±4.93 8.943±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005SG CIL_0005SG_0001 CGP 9:35041095-35073249
CIL_0005SF CIL_0005SF_0001 CGP 9:35056064-35080016

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000502 IDA proteasome complex
GO:0000836 IDA Hrd1p ubiquitin ligase complex
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005811 IDA lipid particle
GO:0005829 IDA cytosol
GO:0006200 IEA ATP catabolic process
GO:0006281 NAS:IEA DNA repair
GO:0006302 IDA double-strand break repair
GO:0006310 IEA DNA recombination
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006888 IEA ER to Golgi vesicle-mediated transport
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0008289 IEA lipid binding
GO:0009378 IEA four-way junction helicase activity
GO:0016567 NAS protein ubiquitination
GO:0016787 IEA hydrolase activity
GO:0016887 TAS:IEA ATPase activity
GO:0018279 IMP protein N-linked glycosylation via asparagine
GO:0019903 IPI protein phosphatase binding
GO:0019904 IPI protein domain specific binding
GO:0019985 IMP translesion synthesis
GO:0030433 TAS ER-associated ubiquitin-dependent protein catabolic process
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0030970 IDA retrograde protein transport, ER to cytosol
GO:0031334 IDA positive regulation of protein complex assembly
GO:0031593 IDA polyubiquitin binding
GO:0032403 IEA protein complex binding
GO:0032436 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034214 IEA protein hexamerization
GO:0035800 IDA deubiquitinase activator activity
GO:0035861 IDA site of double-strand break
GO:0042802 IEA identical protein binding
GO:0042981 TAS regulation of apoptotic process
GO:0043161 NAS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043231 ISS intracellular membrane-bounded organelle
GO:0043234 IEA protein complex
GO:0043531 IEA ADP binding
GO:0044822 IDA poly(A) RNA binding
GO:0045184 TAS establishment of protein localization
GO:0045732 IDA positive regulation of protein catabolic process
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051260 IEA protein homooligomerization
GO:0070062 IDA extracellular vesicular exosome
GO:0070842 IEA aggresome assembly
GO:1903006 IDA positive regulation of protein K63-linked deubiquitination
GO:1903007 IDA positive regulation of Lys63-specific deubiquitinase activity
GO:1990381 IPI ubiquitin-specific protease binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030164 Vcp-001 protein_coding Mus_musculus 0 4054
ENSMUST00000120233 Vcp-rs-001 processed_pseudogene Mus_musculus 0 3243
ENSDART00000023779 vcp-001 protein_coding Danio_rerio 0 1956
ENSMUST00000154541 Vcp-004 processed_transcript Mus_musculus 0 464
ENSMUST00000148182 Vcp-002 processed_transcript Mus_musculus 0 440
ENSMUST00000139127 1700022I11Rik-002 nonsense_mediated_decay Mus_musculus 0 300
ENSMUST00000139843 Vcp-003 processed_transcript Mus_musculus 0 281
ENSMUST00000154423 Vcp-005 processed_transcript Mus_musculus 8.40779e-45 187

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