C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: filamin A, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000360319 FLNA-001 ENSG00000196924 9606 - X:154348526-154371283 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLungMuscleOvaryPlacentaTestisENST00000360319
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENST00000360319 190.217±0.00 220.351±0.00 5.269±0.00 4.106±3.46 64.331±0.00 187.893±0.00 21.653±0.00 9.620±0.00 24.114±0.00 90.366±87.53 50.483±20.28 87.619±76.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L8 CIL_0001L8_0001 CGP X:154295671-154374638
CIL_0001L9 CIL_0001L9_0001 CGP X:154348524-154381523

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001948 IDA glycoprotein binding
GO:0002576 TAS platelet degranulation
GO:0004871 IMP signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007195 IMP adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0008134 IPI transcription factor binding
GO:0015629 IDA actin cytoskeleton
GO:0016020 IDA membrane
GO:0017048 IDA Rho GTPase binding
GO:0017160 IDA Ral GTPase binding
GO:0030168 TAS platelet activation
GO:0031267 IDA small GTPase binding
GO:0031523 IDA Myb complex
GO:0031532 IDA actin cytoskeleton reorganization
GO:0034329 TAS cell junction assembly
GO:0034394 IDA protein localization to cell surface
GO:0034988 IDA Fc-gamma receptor I complex binding
GO:0042177 IMP negative regulation of protein catabolic process
GO:0042384 IMP cilium assembly
GO:0042803 IDA protein homodimerization activity
GO:0042993 IMP positive regulation of transcription factor import into nucleus
GO:0043113 IDA receptor clustering
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0044822 IDA poly(A) RNA binding
GO:0045184 IDA establishment of protein localization
GO:0048365 IDA Rac GTPase binding
GO:0050821 IMP protein stabilization
GO:0051015 IDA actin filament binding
GO:0051220 IMP cytoplasmic sequestering of protein
GO:0051764 IDA actin crosslink formation
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IMP platelet aggregation
GO:0090307 IDA spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000101454 Flna-201 protein_coding Mus_musculus 0 9134
ENSMUST00000114299 Flna-002 protein_coding Mus_musculus 0 9134
ENSMUST00000033699 Flna-003 protein_coding Mus_musculus 0 9029
ENSMUST00000144429 Flna-001 nonsense_mediated_decay Mus_musculus 0 8955
ENSMUST00000130007 Flna-013 protein_coding Mus_musculus 0 5854
ENSMUST00000090474 Flnc-201 protein_coding Mus_musculus 0 2224
ENSMUST00000065090 Flnc-002 protein_coding Mus_musculus 0 2224
ENSDART00000135820 flna-001 protein_coding Danio_rerio 0 1943
ENSDART00000073442 flna-201 protein_coding Danio_rerio 0 1930
ENSMUST00000101617 Flnc-001 protein_coding Mus_musculus 0 1916
ENSMUST00000052678 Flnb-001 protein_coding Mus_musculus 0 839
ENSMUST00000156766 Flna-016 processed_transcript Mus_musculus 0 811
ENSMUST00000141528 Flna-011 retained_intron Mus_musculus 0 787
ENSMUST00000150554 Flna-015 protein_coding Mus_musculus 0 651
ENSMUST00000127463 Flna-014 protein_coding Mus_musculus 0 601
ENSDART00000026492 flncb-201 protein_coding Danio_rerio 0 503
ENSDART00000134286 flncb-001 protein_coding Danio_rerio 0 503
ENSMUST00000124950 Flna-006 retained_intron Mus_musculus 0 496
ENSMUST00000133609 Flna-010 retained_intron Mus_musculus 0 477

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