C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: filamin, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000114299 Flna-002 ENSMUSG00000031328 10090 - X:74223461-74249820 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114299
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114299 99.668±74.99 16.822±3.00 52.342±9.78 172.385±21.23 22.174±3.54 14.674±4.25 3.353±1.83 82.706±19.63 2.327±1.00 182.666±35.96 34.668±24.82 9.278±4.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L8 CIL_0001L8_0002 CGP X:74177259-74249820
CIL_0001L9 CIL_0001L9_0002 CGP X:74223461-74261548

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001837 IGI epithelial to mesenchymal transition
GO:0001948 IEA glycoprotein binding
GO:0003779 TAS actin binding
GO:0004871 IEA signal transducer activity
GO:0005080 IDA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005802 IDA trans-Golgi network
GO:0005829 IEA cytosol
GO:0005884 IEA actin filament
GO:0005886 IEA plasma membrane
GO:0005925 IEA focal adhesion
GO:0007195 IEA adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0008134 IEA transcription factor binding
GO:0015629 IEA actin cytoskeleton
GO:0016020 IEA membrane
GO:0017048 IEA Rho GTPase binding
GO:0017160 IEA Ral GTPase binding
GO:0030036 IGI actin cytoskeleton organization
GO:0030863 IEA cortical cytoskeleton
GO:0031267 IEA small GTPase binding
GO:0031523 ISO Myb complex
GO:0031532 IEA actin cytoskeleton reorganization
GO:0031852 IEA mu-type opioid receptor binding
GO:0034394 IEA protein localization to cell surface
GO:0034988 IEA Fc-gamma receptor I complex binding
GO:0042177 IEA negative regulation of protein catabolic process
GO:0042384 IEA cilium assembly
GO:0042789 IEA mRNA transcription from RNA polymerase II promoter
GO:0042803 IEA protein homodimerization activity
GO:0042993 IEA positive regulation of transcription factor import into nucleus
GO:0043025 IEA neuronal cell body
GO:0043113 IEA receptor clustering
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043198 IEA dendritic shaft
GO:0043234 IEA protein complex
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0044822 IEA poly(A) RNA binding
GO:0045022 IDA early endosome to late endosome transport
GO:0045184 IEA establishment of protein localization
GO:0046332 IEA SMAD binding
GO:0048365 IEA Rac GTPase binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050821 IEA protein stabilization
GO:0051015 IEA actin filament binding
GO:0051220 IEA cytoplasmic sequestering of protein
GO:0051764 IEA actin crosslink formation
GO:0070062 IEA extracellular vesicular exosome
GO:0070527 IEA platelet aggregation
GO:0090307 ISO spindle assembly involved in mitosis
GO:0097440 IEA apical dendrite

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000295956 FLNB-001 protein_coding Homo_sapiens 0 804
ENST00000325888 FLNC-001 protein_coding Homo_sapiens 0 1563
ENST00000344736 FLNA-010 protein_coding Homo_sapiens 0 5928
ENST00000346177 FLNC-002 protein_coding Homo_sapiens 0 1563
ENST00000358537 FLNB-003 protein_coding Homo_sapiens 0 804
ENST00000360319 FLNA-001 protein_coding Homo_sapiens 0 9134
ENST00000369850 FLNA-002 protein_coding Homo_sapiens 0 9084
ENST00000369856 FLNA-022 protein_coding Homo_sapiens 0 8973
ENST00000420627 FLNA-021 nonsense_mediated_decay Homo_sapiens 0 8955
ENST00000422373 FLNA-201 protein_coding Homo_sapiens 0 9190
ENST00000429972 FLNB-005 protein_coding Homo_sapiens 0 804
ENST00000438732 FLNA-015 protein_coding Homo_sapiens 0 601
ENST00000444578 FLNA-016 protein_coding Homo_sapiens 0 665
ENST00000462590 FLNA-009 retained_intron Homo_sapiens 0 608
ENST00000466319 FLNA-005 processed_transcript Homo_sapiens 0 418
ENST00000474072 FLNA-006 retained_intron Homo_sapiens 0 318
ENST00000474358 FLNA-007 retained_intron Homo_sapiens 0 664
ENST00000490882 FLNB-002 protein_coding Homo_sapiens 0 804
ENST00000490936 FLNA-003 retained_intron Homo_sapiens 0 3542
ENST00000498411 FLNA-017 processed_transcript Homo_sapiens 1e-28 130
ENST00000498491 FLNA-008 processed_transcript Homo_sapiens 0 1029
ENST00000610817 FLNA-202 protein_coding Homo_sapiens 0 6654

Loading