C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: filamin, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033699 Flna-003 ENSMUSG00000031328 10090 - X:74223541-74246555 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainMuscleTestisENSMUST00000033699
Transcript ID Brain Muscle Testis
ENSMUST00000033699 8.944±0.00 1.891±0.56 1.022±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001L8 CIL_0001L8_0002 CGP X:74177259-74249820
CIL_0001L9 CIL_0001L9_0002 CGP X:74223461-74261548

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001837 IGI epithelial to mesenchymal transition
GO:0001948 ISS glycoprotein binding
GO:0003779 TAS actin binding
GO:0004871 ISS signal transducer activity
GO:0005080 IDA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005802 IDA trans-Golgi network
GO:0005886 ISS plasma membrane
GO:0007195 ISS adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0008134 ISS transcription factor binding
GO:0017048 ISS Rho GTPase binding
GO:0030036 IGI actin cytoskeleton organization
GO:0031523 ISO Myb complex
GO:0031532 ISS actin cytoskeleton reorganization
GO:0034394 ISS protein localization to cell surface
GO:0034988 ISS Fc-gamma receptor I complex binding
GO:0042177 ISS negative regulation of protein catabolic process
GO:0042993 ISS positive regulation of transcription factor import into nucleus
GO:0043113 ISS receptor clustering
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043433 ISS negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045022 IDA early endosome to late endosome transport
GO:0045184 ISS establishment of protein localization
GO:0048365 ISS Rac GTPase binding
GO:0050821 ISS protein stabilization
GO:0051015 ISS actin filament binding
GO:0051220 ISS cytoplasmic sequestering of protein
GO:0051764 ISS actin crosslink formation
GO:0090307 ISO spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000295956 FLNB-001 protein_coding Homo_sapiens 0 804
ENST00000325888 FLNC-001 protein_coding Homo_sapiens 0 1652
ENST00000344736 FLNA-010 protein_coding Homo_sapiens 0 5823
ENST00000346177 FLNC-002 protein_coding Homo_sapiens 0 1652
ENST00000358537 FLNB-003 protein_coding Homo_sapiens 0 804
ENST00000360319 FLNA-001 protein_coding Homo_sapiens 0 9029
ENST00000369850 FLNA-002 protein_coding Homo_sapiens 0 9226
ENST00000369856 FLNA-022 protein_coding Homo_sapiens 0 9123
ENST00000420627 FLNA-021 nonsense_mediated_decay Homo_sapiens 0 9105
ENST00000422373 FLNA-201 protein_coding Homo_sapiens 0 9077
ENST00000429972 FLNB-005 protein_coding Homo_sapiens 0 804
ENST00000438732 FLNA-015 protein_coding Homo_sapiens 0 601
ENST00000444578 FLNA-016 protein_coding Homo_sapiens 0 665
ENST00000462590 FLNA-009 retained_intron Homo_sapiens 0 608
ENST00000466319 FLNA-005 processed_transcript Homo_sapiens 0 418
ENST00000474072 FLNA-006 retained_intron Homo_sapiens 0 318
ENST00000474358 FLNA-007 retained_intron Homo_sapiens 0 664
ENST00000490882 FLNB-002 protein_coding Homo_sapiens 0 804
ENST00000490936 FLNA-003 retained_intron Homo_sapiens 0 3437
ENST00000498411 FLNA-017 processed_transcript Homo_sapiens 3e-19 99
ENST00000498491 FLNA-008 processed_transcript Homo_sapiens 0 1029
ENST00000610817 FLNA-202 protein_coding Homo_sapiens 0 6796

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