C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MDS1 and EVI1 complex locus
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000468789 MECOM-018 ENSG00000085276 9606 - 3:169084762-169146675 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartLiverMuscleOvaryPlacentaTestisENST00000468789
Transcript ID Brain Breast Heart Liver Muscle Ovary Placenta Testis
ENST00000468789 0.339±0.00 0.845±0.00 0.386±0.00 1.767±0.00 0.336±0.00 2.030±0.00 0.886±0.00 1.166±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SS CIL_0008SS_0001 VISTA 3:168815604-169416752
CIL_000921 CIL_000921_0001 VISTA 3:168940545-169545156
CIL_0007J8 CIL_0007J8_0001 UCNEbase 3:168988832-169608246
CIL_0001ZH CIL_0001ZH_0001 CGP 3:169083499-169769895

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0003677 ISS:IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0016607 IDA nuclear speck
GO:0030154 IEA cell differentiation
GO:0042803 IDA protein homodimerization activity
GO:0043069 IMP negative regulation of programmed cell death
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046329 IMP negative regulation of JNK cascade
GO:0046872 IEA metal ion binding
GO:0051726 IDA regulation of cell cycle
GO:0071425 ISS hematopoietic stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000173495 Mecom-001 protein_coding Mus_musculus 0 4704
ENSMUST00000108270 Mecom-009 protein_coding Mus_musculus 0 4558
ENSMUST00000166001 Mecom-013 protein_coding Mus_musculus 0 3834
ENSMUST00000173899 Mecom-005 protein_coding Mus_musculus 0 3602
ENSMUST00000172697 Mecom-003 protein_coding Mus_musculus 0 3546
ENSMUST00000172754 Mecom-002 nonsense_mediated_decay Mus_musculus 0 2591
ENSMUST00000173059 Mecom-007 protein_coding Mus_musculus 0 1989
ENSMUST00000108271 Mecom-008 protein_coding Mus_musculus 0 1989
ENSMUST00000172694 Mecom-012 protein_coding Mus_musculus 0 1989
ENSMUST00000174413 Mecom-014 protein_coding Mus_musculus 0 1376
ENSMUST00000174428 Mecom-011 retained_intron Mus_musculus 0 965
ENSMUST00000170212 Mecom-010 processed_transcript Mus_musculus 0 961
ENSMUST00000174406 Mecom-015 protein_coding Mus_musculus 0 239

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