C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SMEK homolog 1, suppressor of mek1 (Dictyostelium)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100796 SMEK1 9606 - 14:91457611-91510554 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000554308 SMEK1-005 91461381-91509654 nonsense_mediated_decay
  ENST00000554390 SMEK1-002 91462054-91510480 non_stop_decay
  ENST00000554511 SMEK1-010 91485632-91510300 protein_coding
  ENST00000554574 SMEK1-008 91474641-91481998 retained_intron
  ENST00000554684 SMEK1-001 91457611-91510144 protein_coding
  ENST00000554943 SMEK1-007 91458008-91509763 protein_coding
  ENST00000555029 SMEK1-011 91473349-91509647 protein_coding
  ENST00000555462 SMEK1-003 91458139-91510478 protein_coding
  ENST00000555470 SMEK1-012 91475820-91481873 protein_coding
  ENST00000555718 SMEK1-013 91458859-91466355 processed_transcript
  ENST00000557018 SMEK1-009 91482040-91510554 protein_coding
  ENST00000557382 SMEK1-014 91458330-91461684 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000554308ENST00000554390ENST00000554684ENST00000554943ENST00000555462ENST00000555718ENST00000557382
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000554308 N/A N/A N/A N/A N/A 1.999±0.00 N/A 1.541±0.00 N/A N/A 1.245±0.00 N/A N/A N/A
ENST00000554390 N/A N/A 2.524±0.00 2.899±0.00 6.580±0.00 4.474±0.00 1.448±0.00 2.499±0.00 2.361±0.00 6.575±0.00 1.484±0.00 7.413±3.60 8.376±5.74 30.459±0.00
ENST00000554684 3.447±0.00 2.815±0.00 N/A 2.210±0.26 2.836±0.00 2.082±0.07 4.026±0.00 5.390±3.93 2.262±1.21 3.736±0.00 N/A 5.534±2.64 3.308±0.00 7.637±0.00
ENST00000554943 1.969±0.00 4.991±0.00 N/A 1.168±0.19 2.999±0.06 2.740±0.00 1.778±1.24 N/A 2.050±0.00 2.092±0.17 1.283±0.87 3.257±1.32 4.692±1.01 9.262±3.47
ENST00000555462 2.711±0.00 4.033±0.00 2.148±0.00 2.008±0.00 2.806±0.00 2.448±0.26 N/A 4.534±0.00 1.251±0.00 4.598±0.00 1.490±0.39 4.840±2.68 6.471±0.00 9.847±6.26
ENST00000555718 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.769±0.00 N/A N/A N/A
ENST00000557382 8.790±0.00 22.989±0.00 N/A 10.385±0.00 8.131±0.00 13.017±0.00 8.426±0.00 10.524±4.36 6.115±0.00 10.593±0.00 3.816±1.76 20.786±0.00 N/A 18.712±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000AE CIL_0000AE_0001 CGP 14:91271323-91510554
CIL_0000AH CIL_0000AH_0001 CGP 14:91457611-91780707

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006470 IEA protein dephosphorylation
GO:0030289 IEA protein phosphatase 4 complex
GO:0045722 IEA positive regulation of gluconeogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042187 smek1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) protein_coding Danio_rerio
ENSMUSG00000041846 Smek1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) protein_coding Mus_musculus

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