C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TAR DNA binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120948 TARDBP 9606 + 1:11012344-11026420 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000240185 TARDBP-001 11012400-11026420 protein_coding
  ENST00000315091 TARDBP-003 11013716-11024183 protein_coding
  ENST00000439080 TARDBP-011 11012653-11022858 nonsense_mediated_decay
  ENST00000472476 TARDBP-006 11012654-11022176 nonsense_mediated_decay
  ENST00000473118 TARDBP-004 11012344-11020489 protein_coding
  ENST00000473869 TARDBP-002 11013716-11025019 nonsense_mediated_decay
  ENST00000476201 TARDBP-005 11012654-11020589 protein_coding
  ENST00000477447 TARDBP-007 11020587-11025207 nonsense_mediated_decay
  ENST00000480464 TARDBP-009 11023929-11025492 processed_transcript
  ENST00000496840 TARDBP-008 11023198-11025739 nonsense_mediated_decay
  ENST00000610369 TARDBP-022 11018853-11024043 protein_coding
  ENST00000611008 TARDBP-026 11022818-11025492 processed_transcript
  ENST00000611963 TARDBP-020 11016966-11024193 nonsense_mediated_decay
  ENST00000613177 TARDBP-027 11023045-11025203 processed_transcript
  ENST00000613864 TARDBP-014 11012654-11018453 processed_transcript
  ENST00000614494 TARDBP-023 11020433-11024183 nonsense_mediated_decay
  ENST00000616545 TARDBP-013 11013728-11023341 protein_coding
  ENST00000617172 TARDBP-019 11016865-11023590 protein_coding
  ENST00000617757 TARDBP-028 11023323-11024152 processed_transcript
  ENST00000618606 TARDBP-015 11016878-11019186 retained_intron
  ENST00000619555 TARDBP-018 11018780-11024184 nonsense_mediated_decay
  ENST00000620505 TARDBP-024 11022308-11025221 nonsense_mediated_decay
  ENST00000620632 TARDBP-021 11018780-11024043 nonsense_mediated_decay
  ENST00000621573 TARDBP-025 11022548-11024273 nonsense_mediated_decay
  ENST00000621715 TARDBP-016 11012670-11022310 protein_coding
  ENST00000621790 TARDBP-012 11013728-11023341 protein_coding
  ENST00000622057 TARDBP-017 11016859-11023287 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000240185ENST00000315091ENST00000439080ENST00000473118ENST00000473869ENST00000611008ENST00000613864ENST00000616545ENST00000617172ENST00000617757ENST00000621573ENST00000621715
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000240185 N/A N/A 1.520±0.00 1.963±0.56 2.862±0.54 1.741±0.00 0.514±0.00 4.388±0.00 1.089±0.00 3.043±0.00 N/A 4.490±1.56 N/A 6.064±0.00
ENST00000315091 27.214±0.00 32.965±0.00 2.167±0.00 9.024±6.89 23.912±0.00 16.599±13.19 15.673±0.00 29.118±0.00 N/A 15.946±11.17 9.012±6.87 44.512±7.27 28.377±2.51 31.185±6.40
ENST00000439080 23.679±0.00 23.591±0.00 3.250±0.00 16.309±0.00 13.950±0.00 19.037±0.00 15.212±0.00 23.064±0.00 2.501±0.00 16.522±0.00 7.660±5.67 26.597±0.00 22.622±5.65 26.258±0.98
ENST00000473118 N/A N/A 6.391±0.00 N/A N/A N/A N/A N/A 7.989±0.00 N/A N/A 8.703±0.00 N/A N/A
ENST00000473869 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.554±0.00 N/A N/A N/A
ENST00000611008 N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.388±0.00 N/A N/A N/A N/A
ENST00000613864 N/A N/A N/A 6.847±0.00 N/A 12.893±0.00 5.836±0.00 N/A 7.351±0.00 11.248±0.00 N/A 8.939±0.00 N/A N/A
ENST00000616545 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.145±0.00 N/A N/A N/A
ENST00000617172 N/A N/A N/A N/A 13.606±0.00 5.563±0.00 N/A N/A 3.265±0.00 N/A N/A 5.704±0.00 N/A 22.440±0.00
ENST00000617757 N/A N/A N/A N/A N/A 49.632±0.00 N/A N/A N/A N/A N/A 126.848±0.00 102.423±0.00 83.383±0.00
ENST00000621573 16.184±0.00 N/A N/A N/A 12.400±0.00 15.296±0.00 10.874±0.00 21.409±0.00 N/A 12.624±0.00 9.528±0.00 N/A 17.866±0.31 21.012±0.00
ENST00000621715 N/A N/A N/A N/A N/A N/A 2.545±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00082Y CIL_00082Y_0001 VISTA 1:10421182-11021687
CIL_0008S2 CIL_0008S2_0001 VISTA 1:10435049-11039184
CIL_0008RU CIL_0008RU_0001 VISTA 1:10491513-11092116
CIL_0008JG CIL_0008JG_0001 VISTA 1:10565145-11165671
CIL_0008JY CIL_0008JY_0001 VISTA 1:10605072-11206087
CIL_00019T CIL_00019T_0002 CGP 1:10946471-11026420

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003676 IEA nucleic acid binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003723 IDA RNA binding
GO:0003730 IDA mRNA 3'-UTR binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005726 IEA perichromatin fibrils
GO:0005737 IEA cytoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006397 IEA mRNA processing
GO:0008219 IEA cell death
GO:0008380 IDA RNA splicing
GO:0016607 IEA nuclear speck
GO:0032024 IEA positive regulation of insulin secretion
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0035061 IEA interchromatin granule
GO:0042802 IPI identical protein binding
GO:0043922 IDA negative regulation by host of viral transcription
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0070935 IDA 3'-UTR-mediated mRNA stabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004452 tardbpl TAR DNA binding protein, like protein_coding Danio_rerio
ENSDARG00000040031 tardbp TAR DNA binding protein protein_coding Danio_rerio
ENSMUSG00000041459 Tardbp TAR DNA binding protein protein_coding Mus_musculus

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