C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TAR DNA binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041459 Tardbp 10090 - 4:148612382-148627019 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045180 Tardbp-002 148615919-148626765 nonsense_mediated_decay
  ENSMUST00000084125 Tardbp-001 148612382-148627019 protein_coding
  ENSMUST00000095719 Tardbp-007 148617554-148625362 protein_coding
  ENSMUST00000105699 Tardbp-006 148616726-148626758 protein_coding
  ENSMUST00000105700 Tardbp-003 148617554-148625362 protein_coding
  ENSMUST00000105702 Tardbp-201 148612382-148626996 protein_coding
  ENSMUST00000140897 Tardbp-004 148616721-148620690 nonsense_mediated_decay
  ENSMUST00000147391 Tardbp-005 148616636-148618367 nonsense_mediated_decay
  ENSMUST00000165113 Tardbp-202 148612382-148626996 protein_coding
  ENSMUST00000172073 Tardbp-203 148612382-148626996 protein_coding
  ENSMUST00000185673 Tardbp-014 148620688-148626323 protein_coding
  ENSMUST00000185824 Tardbp-016 148617608-148622097 protein_coding
  ENSMUST00000186317 Tardbp-027 148615759-148617852 processed_transcript
  ENSMUST00000186711 Tardbp-025 148617046-148618680 protein_coding
  ENSMUST00000186729 Tardbp-023 148612485-148619276 nonsense_mediated_decay
  ENSMUST00000186947 Tardbp-015 148618605-148626754 protein_coding
  ENSMUST00000187937 Tardbp-028 148615610-148616980 processed_transcript
  ENSMUST00000187939 Tardbp-019 148616863-148620612 protein_coding
  ENSMUST00000188134 Tardbp-024 148612387-148626762 nonsense_mediated_decay
  ENSMUST00000188380 Tardbp-029 148612388-148616138 processed_transcript
  ENSMUST00000188488 Tardbp-022 148612388-148618771 protein_coding
  ENSMUST00000189041 Tardbp-026 148615466-148618075 processed_transcript
  ENSMUST00000189048 Tardbp-012 148617451-148625362 protein_coding
  ENSMUST00000190287 Tardbp-020 148616726-148619350 nonsense_mediated_decay
  ENSMUST00000190478 Tardbp-013 148625085-148626758 retained_intron
  ENSMUST00000190552 Tardbp-017 148616716-148621990 nonsense_mediated_decay
  ENSMUST00000190630 Tardbp-021 148617308-148619286 protein_coding
  ENSMUST00000190696 Tardbp-011 148618035-148626770 nonsense_mediated_decay
  ENSMUST00000191378 Tardbp-018 148616725-148620685 nonsense_mediated_decay
  ENSMUST00000191450 Tardbp-009 148616725-148626758 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045180ENSMUST00000084125ENSMUST00000105699ENSMUST00000105702ENSMUST00000147391ENSMUST00000165113ENSMUST00000186711ENSMUST00000190478ENSMUST00000190696
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045180 N/A N/A N/A 12.038±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000084125 14.515±5.40 6.444±1.41 24.433±5.83 26.245±7.09 12.930±2.98 9.469±1.79 3.979±0.33 10.278±2.82 18.666±3.95 16.300±0.82 6.684±0.58 11.331±4.05 9.999±4.16 8.653±0.07
ENSMUST00000105699 N/A N/A 46.005±12.16 29.722±12.19 N/A N/A 5.980±1.11 9.827±0.32 65.995±13.58 N/A 21.053±1.54 43.626±7.30 52.393±17.94 15.318±1.79
ENSMUST00000105702 N/A N/A N/A 5.287±0.00 4.724±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000147391 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 27.694±3.44 N/A
ENSMUST00000165113 N/A N/A N/A N/A 6.702±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000186711 N/A N/A N/A 78.030±12.42 N/A N/A 15.206±1.36 N/A 127.835±6.24 N/A N/A 128.695±63.10 124.788±86.54 138.780±0.00
ENSMUST00000190478 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 403.221±0.00 681.567±97.85 N/A
ENSMUST00000190696 21.873±4.39 9.164±1.53 N/A 36.465±6.74 N/A 9.054±0.31 10.149±0.56 15.885±0.83 68.936±7.94 22.667±3.73 16.692±0.00 32.733±23.99 58.559±20.39 27.975±11.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JY CIL_0008JY_0002 VISTA 4:148408124-149009196
CIL_0008JG CIL_0008JG_0002 VISTA 4:148444314-149044861
CIL_0008RU CIL_0008RU_0002 VISTA 4:148508781-149109416
CIL_0008S2 CIL_0008S2_0002 VISTA 4:148555953-149160332
CIL_00082Y CIL_00082Y_0002 VISTA 4:148576108-149176659
CIL_00085P CIL_00085P_0002 VISTA 4:148597228-149198219

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003676 IEA nucleic acid binding
GO:0003690 IEA double-stranded DNA binding
GO:0003723 IEA RNA binding
GO:0003730 IEA mRNA 3'-UTR binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005726 IEA perichromatin fibrils
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0008380 IEA RNA splicing
GO:0016607 IEA nuclear speck
GO:0032024 IEA positive regulation of insulin secretion
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0035061 IEA interchromatin granule
GO:0042802 IEA identical protein binding
GO:0043922 IEA negative regulation by host of viral transcription
GO:0044822 IEA poly(A) RNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070935 IEA 3'-UTR-mediated mRNA stabilization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004452 tardbpl TAR DNA binding protein, like protein_coding Danio_rerio
ENSDARG00000040031 tardbp TAR DNA binding protein protein_coding Danio_rerio
ENSG00000120948 TARDBP TAR DNA binding protein protein_coding Homo_sapiens

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