C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lactate dehydrogenase A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134333 LDHA 9606 + 11:18394388-18408425 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227157 LDHA-003 18394586-18408218 protein_coding
  ENST00000375710 LDHA-023 18399726-18407584 retained_intron
  ENST00000379412 LDHA-005 18396278-18407847 protein_coding
  ENST00000396222 LDHA-002 18394562-18408218 protein_coding
  ENST00000422447 LDHA-001 18394388-18408425 protein_coding
  ENST00000430553 LDHA-010 18394562-18407667 protein_coding
  ENST00000460405 LDHA-008 18398866-18403784 retained_intron
  ENST00000469976 LDHA-006 18394561-18397398 retained_intron
  ENST00000478970 LDHA-009 18394612-18401025 protein_coding
  ENST00000486690 LDHA-017 18396818-18405495 nonsense_mediated_decay
  ENST00000494573 LDHA-007 18394563-18400360 retained_intron
  ENST00000495052 LDHA-004 18394704-18400936 protein_coding
  ENST00000535451 LDHA-014 18394563-18399521 protein_coding
  ENST00000536528 LDHA-021 18394563-18403811 nonsense_mediated_decay
  ENST00000537296 LDHA-022 18398630-18405574 retained_intron
  ENST00000538451 LDHA-024 18402535-18407740 retained_intron
  ENST00000539814 LDHA-016 18394563-18400934 nonsense_mediated_decay
  ENST00000540430 LDHA-201 18396266-18408218 protein_coding
  ENST00000541097 LDHA-019 18394563-18407158 nonsense_mediated_decay
  ENST00000542179 LDHA-020 18396554-18407281 protein_coding
  ENST00000543445 LDHA-013 18394560-18402891 protein_coding
  ENST00000543695 LDHA-015 18394563-18403759 nonsense_mediated_decay
  ENST00000545215 LDHA-011 18394563-18407642 nonsense_mediated_decay
  ENST00000545467 LDHA-018 18394562-18400872 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227157ENST00000379412ENST00000396222ENST00000422447ENST00000430553ENST00000486690ENST00000536528ENST00000542179ENST00000545215
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227157 N/A N/A 5.631±0.00 N/A N/A 7.921±0.00 N/A N/A N/A N/A 20.537±0.00 N/A N/A N/A
ENST00000379412 86.087±0.00 57.218±0.00 N/A 45.787±0.00 60.097±0.00 71.105±0.00 25.103±0.00 97.913±0.00 N/A 51.816±0.00 22.753±0.00 78.699±28.37 41.016±13.93 29.533±12.50
ENST00000396222 N/A N/A 6.526±0.00 28.468±0.00 18.992±0.00 12.519±0.00 8.054±0.00 37.384±0.00 27.746±0.00 21.722±0.00 44.437±0.00 23.221±0.20 36.776±3.64 N/A
ENST00000422447 N/A N/A 4.715±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000430553 N/A N/A 6.576±0.00 27.995±0.00 25.500±0.00 48.461±26.58 9.371±0.00 67.582±0.00 36.614±0.00 32.177±0.00 104.912±0.00 68.265±27.35 107.846±0.00 55.152±0.00
ENST00000486690 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 252.364±0.00 224.640±0.00 103.493±0.00
ENST00000536528 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 276.120±0.00 N/A 119.643±0.00
ENST00000542179 N/A N/A N/A N/A 11.823±0.00 N/A N/A N/A N/A N/A N/A N/A 41.739±0.00 N/A
ENST00000545215 219.482±0.00 155.820±0.00 7.122±0.00 35.016±11.28 135.052±124.00 81.902±61.45 11.827±6.93 116.293±0.00 122.736±0.00 43.483±0.00 29.575±2.23 28.695±0.00 37.081±0.00 110.172±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000445 CIL_000445_0001 CGP 11:18322295-18408425
CIL_000369 CIL_000369_0001 CGP 11:18394388-18452058

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004459 NAS L-lactate dehydrogenase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0005975 IEA carbohydrate metabolic process
GO:0006090 TAS pyruvate metabolic process
GO:0006096 NAS glycolytic process
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0021762 IEP substantia nigra development
GO:0031668 IEA cellular response to extracellular stimulus
GO:0035686 IEA sperm fibrous sheath
GO:0044237 TAS cellular metabolic process
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040856 ldha lactate dehydrogenase A4 protein_coding Danio_rerio
ENSMUSG00000063229 Ldha lactate dehydrogenase A protein_coding Mus_musculus

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