C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000150991 UBC 9606 - 12:124911604-124917368 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000339647 UBC-001 124911648-124915147 protein_coding
  ENST00000535131 UBC-015 124913323-124914079 protein_coding
  ENST00000535859 UBC-013 124913404-124914304 protein_coding
  ENST00000536661 UBC-010 124913587-124915031 processed_transcript
  ENST00000536769 UBC-007 124911604-124915348 protein_coding
  ENST00000538617 UBC-003 124911646-124915303 protein_coding
  ENST00000540351 UBC-009 124913290-124914141 protein_coding
  ENST00000540700 UBC-011 124913370-124914591 protein_coding
  ENST00000541272 UBC-016 124913035-124914074 protein_coding
  ENST00000541645 UBC-014 124913306-124914119 protein_coding
  ENST00000542416 UBC-008 124913587-124917368 protein_coding
  ENST00000544481 UBC-017 124913350-124914065 processed_transcript
  ENST00000546120 UBC-201 124911704-124914601 protein_coding
  ENST00000546271 UBC-012 124913362-124914443 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000339647ENST00000536769ENST00000538617ENST00000541272ENST00000546120
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000339647 98.746±0.00 79.910±0.00 N/A 113.515±0.00 92.181±6.79 111.088±0.00 72.296±0.00 77.357±11.07 64.832±29.95 133.483±24.64 136.901±0.00 49.130±19.24 N/A 148.514±45.83
ENST00000536769 N/A 24.412±0.00 N/A N/A N/A N/A N/A N/A N/A 17.527±0.00 N/A N/A N/A N/A
ENST00000538617 172.446±0.00 164.947±0.00 36.555±0.00 158.878±66.51 129.904±45.13 132.715±84.40 90.402±38.27 90.619±40.62 72.843±3.06 218.487±136.06 181.432±63.45 103.730±74.78 281.890±66.29 198.304±49.00
ENST00000541272 126.886±0.00 119.208±0.00 N/A 162.420±0.00 125.732±0.00 161.089±0.00 161.913±0.00 124.512±0.00 51.238±0.00 346.396±0.00 254.301±0.00 N/A N/A 198.206±0.00
ENST00000546120 125.435±0.00 142.031±0.00 N/A 113.148±0.00 114.612±0.00 155.921±0.00 96.257±0.00 119.916±0.00 44.151±0.00 258.870±0.00 203.963±0.00 127.324±56.34 139.389±45.04 127.942±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00006N CIL_00006N_0002 CGP 12:124776856-124917368

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000187 TAS activation of MAPK activity
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0002020 IPI protease binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0005978 TAS glycogen biosynthetic process
GO:0006006 TAS glucose metabolic process
GO:0006281 TAS DNA repair
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0007220 TAS Notch receptor processing
GO:0007249 TAS I-kappaB kinase/NF-kappaB signaling
GO:0007254 TAS JNK cascade
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0010008 TAS endosome membrane
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016197 TAS endosomal transport
GO:0019058 TAS viral life cycle
GO:0019068 TAS virion assembly
GO:0019082 TAS viral protein processing
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030512 TAS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030666 TAS endocytic vesicle membrane
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0032479 TAS regulation of type I interferon production
GO:0032480 TAS negative regulation of type I interferon production
GO:0032481 TAS positive regulation of type I interferon production
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0034220 TAS ion transmembrane transport
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043123 TAS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050852 TAS T cell receptor signaling pathway
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity
GO:0051403 TAS stress-activated MAPK cascade
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0055085 TAS transmembrane transport
GO:0061024 TAS membrane organization
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 IDA extracellular vesicular exosome
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway
GO:0071456 TAS cellular response to hypoxia
GO:0075733 TAS intracellular transport of virus
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002369 UBC protein_coding Danio_rerio
ENSDARG00000067755 ubc ubiquitin C protein_coding Danio_rerio
ENSMUSG00000008348 Ubc ubiquitin C protein_coding Mus_musculus
ENSMUSG00000019505 Ubb ubiquitin B protein_coding Mus_musculus

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