C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: autophagy related 4B, cysteine peptidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168397 ATG4B 9606 + 2:241637213-241673857 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344376 ATG4B-005 241651007-241672592 nonsense_mediated_decay
  ENST00000400771 ATG4B-025 241637710-241668221 protein_coding
  ENST00000400772 ATG4B-011 241637626-241655330 nonsense_mediated_decay
  ENST00000402096 ATG4B-006 241637612-241672628 protein_coding
  ENST00000404914 ATG4B-002 241637612-241673857 protein_coding
  ENST00000405546 ATG4B-001 241637213-241673854 protein_coding
  ENST00000415107 ATG4B-022 241637710-241653524 nonsense_mediated_decay
  ENST00000419606 ATG4B-015 241637693-241655306 protein_coding
  ENST00000425239 ATG4B-023 241637707-241659448 protein_coding
  ENST00000428861 ATG4B-027 241666596-241671366 protein_coding
  ENST00000429899 ATG4B-026 241653467-241666769 protein_coding
  ENST00000430617 ATG4B-020 241637729-241659187 protein_coding
  ENST00000460211 ATG4B-028 241667812-241671569 retained_intron
  ENST00000465399 ATG4B-016 241637693-241655444 retained_intron
  ENST00000468018 ATG4B-021 241637697-241659200 retained_intron
  ENST00000475195 ATG4B-014 241637693-241655002 retained_intron
  ENST00000475693 ATG4B-008 241668259-241673849 retained_intron
  ENST00000479554 ATG4B-013 241637693-241654705 retained_intron
  ENST00000479941 ATG4B-030 241668169-241668860 retained_intron
  ENST00000482507 ATG4B-004 241637698-241672631 retained_intron
  ENST00000483778 ATG4B-012 241637662-241659772 retained_intron
  ENST00000491867 ATG4B-010 241637620-241653333 processed_transcript
  ENST00000493618 ATG4B-024 241637706-241659611 retained_intron
  ENST00000494132 ATG4B-029 241670561-241671917 retained_intron
  ENST00000494465 ATG4B-003 241637635-241672599 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344376ENST00000402096ENST00000404914ENST00000405546ENST00000419606ENST00000465399ENST00000475195ENST00000475693ENST00000482507
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344376 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.051±3.49 28.281±0.00
ENST00000402096 N/A N/A N/A N/A N/A N/A N/A 4.686±0.00 N/A N/A N/A N/A 18.336±0.00
ENST00000404914 5.561±0.00 1.140±0.00 6.460±3.53 3.419±2.15 5.735±0.00 2.570±1.94 9.526±0.00 2.515±0.48 2.912±0.95 N/A 10.087±5.98 11.383±0.00 N/A
ENST00000405546 N/A N/A N/A N/A N/A N/A 0.831±0.00 N/A N/A N/A N/A N/A N/A
ENST00000419606 N/A N/A N/A N/A N/A N/A 2.970±0.00 N/A N/A N/A N/A N/A N/A
ENST00000465399 N/A 8.595±0.00 11.727±0.00 12.513±0.00 9.724±0.00 2.531±0.00 6.200±0.00 9.821±0.00 9.547±0.00 5.485±0.00 6.438±0.00 N/A N/A
ENST00000475195 N/A N/A N/A N/A 6.798±0.00 N/A N/A N/A N/A N/A 5.942±0.00 N/A N/A
ENST00000475693 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.242±0.00 N/A N/A N/A
ENST00000482507 9.252±0.00 N/A N/A N/A N/A N/A 6.630±0.00 3.415±0.00 6.914±0.00 N/A 24.089±11.44 N/A 20.382±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004U9 CIL_0004U9_0002 CGP 2:241558721-241637449
CIL_0003ST CIL_0003ST_0001 CGP 2:241584405-241673857
CIL_0004UA CIL_0004UA_0002 CGP 2:241637213-241686991

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IGI autophagic vacuole assembly
GO:0004175 IDA endopeptidase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0006508 IEA proteolysis
GO:0006914 IEA autophagy
GO:0008233 IEA peptidase activity
GO:0008234 IEA cysteine-type peptidase activity
GO:0010508 IDA positive regulation of autophagy
GO:0015031 IEA protein transport
GO:0045732 IEA positive regulation of protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052104 atg4b ATG4 autophagy related 4 homolog B (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000026280 Atg4b autophagy related 4B, cysteine peptidase protein_coding Mus_musculus

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