C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: autophagy related 4B, cysteine peptidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026280 Atg4b 10090 + 1:93751500-93790610 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027502 Atg4b-001 93754905-93790610 protein_coding
  ENSMUST00000135762 Atg4b-002 93755045-93788179 retained_intron
  ENSMUST00000149436 Atg4b-003 93751500-93775683 protein_coding
  ENSMUST00000185482 Atg4b-010 93755035-93784923 nonsense_mediated_decay
  ENSMUST00000185754 Atg4b-008 93786218-93787899 retained_intron
  ENSMUST00000186001 Atg4b-006 93768077-93775448 retained_intron
  ENSMUST00000186124 Atg4b-009 93785583-93786580 retained_intron
  ENSMUST00000186811 Atg4b-011 93784797-93787877 nonsense_mediated_decay
  ENSMUST00000187824 Atg4b-005 93754988-93778288 protein_coding
  ENSMUST00000189152 Atg4b-004 93755162-93768100 processed_transcript
  ENSMUST00000189872 Atg4b-007 93784343-93785081 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027502ENSMUST00000135762ENSMUST00000149436ENSMUST00000185482ENSMUST00000186811
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027502 5.623±0.45 6.860±1.54 14.957±3.39 12.981±5.98 3.649±0.78 7.743±1.55 2.664±0.30 5.479±0.90 7.962±4.13 5.199±0.52 3.211±0.39 5.394±1.96 7.334±5.70 3.690±2.31
ENSMUST00000135762 3.382±0.82 7.071±1.35 1.840±0.14 11.245±0.38 4.449±0.81 3.029±0.56 1.169±0.08 1.793±0.50 2.116±0.60 4.132±0.34 0.671±0.06 5.964±2.29 2.182±0.03 2.506±0.28
ENSMUST00000149436 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 36.281±12.09 12.325±0.00
ENSMUST00000185482 N/A 26.195±2.49 9.244±1.25 16.426±0.00 11.756±0.30 13.823±1.75 5.328±0.00 10.799±0.00 9.684±4.04 N/A 4.702±0.86 21.681±2.04 27.845±10.67 7.397±1.83
ENSMUST00000186811 N/A N/A N/A 31.524±0.00 N/A N/A N/A N/A N/A N/A N/A 37.730±0.00 45.426±5.83 11.230±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004U9 CIL_0004U9_0003 CGP 1:93685660-93754864
CIL_0003ST CIL_0003ST_0002 CGP 1:93701935-93790610
CIL_0004UA CIL_0004UA_0003 CGP 1:93751500-93801934

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IEA autophagic vacuole assembly
GO:0004175 IEA endopeptidase activity
GO:0004197 ISS cysteine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0006508 IEA proteolysis
GO:0006914 ISS autophagy
GO:0008233 IDA peptidase activity
GO:0008234 ISO cysteine-type peptidase activity
GO:0010508 IEA positive regulation of autophagy
GO:0015031 IEA protein transport
GO:0045732 IEA positive regulation of protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052104 atg4b ATG4 autophagy related 4 homolog B (S. cerevisiae) protein_coding Danio_rerio
ENSG00000168397 ATG4B autophagy related 4B, cysteine peptidase protein_coding Homo_sapiens

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